My fish report reads:
These FISH studies detected multiple abnormalities in interphase nuclei including an extra cope of the IGH signal at 14q32, gain of MAF signal, and gain of TP53 signal.
Is a gain of TP53 signal does that mean a deletion? If there is a gain of signal is that the same as deletion 17p?
Does MAF = 16q23? Is a gain of signal good or does signal detected many it is present and bad?
If the abnormalities are only found in a maximum of 11.5% of cells does that improve the negative overall prognostic or does simply having them determine prognosis independent of the quantity found?
Does TP53 signal trump trisomy/hyperdiploidy in terms of survival?
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