Thrombocytosis

[sherrifortier]

So, I have been getting the run-around for nearly 3 years now.
I am 39 years old. Complete hysterectomy 14 years ago. No estrogen therapy as I have fibrous breast tissue.
My recent blood work platelets 559,000 wbc 13.9 and have a swollen lymph node. I am consistently tired and achy as if I have a chronic flu. Low grade fever that comes and goes and extreme nausea (taking Zofran, Maxeran & gravol for this).
I also have tiny red pin sized spots all over my body. They are not itchy, or raised, but more appear all the time. (They look similar to beauty spots/freckles but are red)
I tested positive for H.Pylori back in Novemeber, but as my alergies prevent any antibiotic treatment, I could only take Tecta & Pepto Bismol for treatment.
I have a gastroscopy consult this month.
Any suggestions as to the cause and treatments or exams to pursue would be greatly appreciated.

[Ken_PA]

Hi, there is  thread right next to yours from smg145 about bloodwork values; she also had gallbladder problems from probable autoimmunity (lupus).

[sherrifortier]

Update:
Had an emergency gallbladder removal through laparoscopy on the 9th of June. Was terribly ill, due to a gallstone causing a blocked duct as well as a perforation.
I see the NEW hematologist on the 31st of this month. (For a second opinion) Yay!!!
Also, recent bloodwork shows not only elevated WBC and platelets (both as per the usual) but now elevated polymorphonuclear leukocytes, which is a new finding.
Curious as to whether others have had similar findings, and what their diagnosis / prognosis is.
Thanks

[sherrifortier]

At that time it showed 5 minutes

[Ken_PA]

Did it show prolonged bleed time?

[sherrifortier]

I did have a bleed time test done about 18 months ago, when I was getting the iron infusions done.

[Ken_PA]

Are you getting your INR tested (clotting time)?


A deficiency or dysfunction of clotting factors might indicate something about the liver (where the factors are manufactured).

But if the clotting factors seem okay, then that would tend to implicate dysfunctional platelets.

Platelets at 559 aren't that high, and in fact the normal range is just telling what the averages are.

[sherrifortier]

I am taking C-Boost (1250% daily vitamin C in 1 cup) with my body by vi shakes with no difference to the h-pylori. But I am appreciative of any input and help at this stage.
I too thought the petechia and blood thinners combo was strange

[Ken_PA]

Hi, I remember the thrombocytosis and petechiae from some time ago. IIRC, your doc wanted you to take blood thinners even while you had the petechiae?    (which seemed wrong to me)


Btw, there is some evidence that plain vitamin C can eliminate H Pylori, in some people... maybe 1/3 of cases. Also, olive leaf extract might help killing that off. (I don't usually think that alternative remedies work much, but those might be worth a try.)

I'll see if I can find that vit C study for you.