Aa
A
A
Close
Avatar_universal
blood anomaly
My nephew was diagnosed with pelger-huet anomaly.  Could you please tell me exactly what this is and if it is life threatening.   Also, is it inherited?  Thanks
Cancel
1 Answers
Page 1 of 1
Avatar_universal
Pelger Huet anomaly (PHA)involves a structural defect in white blood cells. The white blood cells appear abnormal but generally remain functionality, and hence is not life threatening. There is however, a pseudo Pelger Huet anomaly which occurs in some forms of leukemia which must be distinguished, as this would have a different outcome.
Pelger Huet anomaly is inheritable. Those with a single copy (meaning either maternal or paternal gene is a defective PHA trait) generally have no symptoms but will have abnormal looking cells when examined. Those having 2 defective copies may have skeletal abnormalities, developmental delay, and risk for seizures.
Comment
Cancel
Avatar_universal
Comment
Comment
Submit Comment
Your Answer
Avatar_universal
Answer
Know how to answer? Tap here to leave your answer...
Answer
blood anomaly
Submit Answer
A
A
Blank
Weight Tracker
Weight Tracker
Start Tracking Now
Leukemia & Lymphoma Community Resources