chromosomes and AML

I recently discovered the connection between a balanced translocation of chromosomes 11 and 17 (q23; q21) and AML. I am wondering - does this mean that someone with that exact translocation and breakpoint - t(11;17) (q23;q21) will definately develop AML? If not, how likely is it? Also, if a person has the same balanced translocation of 11 and 17 but with the breakpoints slighlty different (q23;q11.5) how likely is that to make a difference in predicting the occurence of AML? Finally, why wold someone have a CVS test that found t(11;17) (q23;q21) and then a karyotype show t11;17) (q23;q11.2)? The report stated, "The breakpoiint on the chromosome 17 long arm differs slightly from that listed for the CVS; this most likely represents the higher banding resolution obtained on the blood sample." So which is the correct one? Any help will be appreciated!

[Dnmh]

This one is way out of my league! Maybe someone else will post a reply?