Apap misuse

I have been ingesting Percocet 5/325mg taking about 1k apap every 5 hours for the past few weeks. Do I need to worry about permanent liver damage?  I am taking under 4k acetaminophen in 24 hrs but the dosing is only 3x daily so about 3200mg in ten hours since I do 975 initial then 5 hours later and then once more. Thanks in advance.

[Paderla Anitha, DNB]

Hello and hope you are doing well.

Acetaminophen can cause liver damage. For the average healthy adult, the recommended maximum dose of acetaminophen over a 24 hour period is four grams (4000 mg).  A person who drinks more than two alcoholic beverages per day, however, should not take more than two grams of acetaminophen over 24 hour.

Also, a single dose of 7 to 10 grams of acetaminophen can cause liver injury in the average healthy adult.

Hope this helped and do keep us posted.