Blood Work Reports

63 year ol male, runner, great health

Recent Blood Work Report:
GLOBULIN 1.6
ALBUMIN/GLOBULIN RATIO 2.8
ALKALINE PHOSPHATASE 35
AST 50

Can anyone help me out with what this might mean?

[mikesimon]

I am going off the top of my head and I am not a doctor. I can only tell you what occurs to me and I very well could be totally wrong.

Your globulin looks low to me.
You albumin looks ok.
Your A/G ratio is probably a bit high because your globulin (the divisor) is low.
Your AST may be slightly elevated ( the reference range on my Quest sheet shows 10 - 35). Not high enough to panic about but enough to warrant more tests. AST is associated with the liver but not as specifically as ALT is.
Your alkaline phosphatase looks within normal range.

I am not sure what all this suggests but I think you might investigate your liver and renal function. Initially I would think that additional blood work and a urine test might be appropriate.

If, as I believe, your A/G ratio is high then I think that you might have increased possibility of blood clots. I think I read this somewhere but I don't have the site.

I just found this on the MedHelp Gastro site.

"Dear Lisa:

The albumin/globulin ratio is the calculation of serum albumin compare to serum globulin level to determine whether there is an overproduction or underproduction of gamma-globulin. A low A/G ratio may be due to overproduction of gamma-globulin (monoclonal/polyclonal gammopathy, multiple myeloma or autoimmune diseases etc.) or due to low albumin (low production as in cirrhosis or excessive loss as in nephrotic syndrome or protein losing enteropathy etc.).In contrast, if the A/G ratio is high then one should look for diseases with low gamma-globulin production such as agammaglobuminemia. Often a serum electrophoresis or immunoelectrophoresis can determine a more specific abnormality."

I wish you good luck Everest. I'm sorry that I can't be of more help.

Mike