Liver Disorders Community
Elevated liver enzymes.
About This Community:

This support community is for discussions and support relating to liver disorders.

Font Size:
A
A
A
Background:
Blank
Blank
Blank
Blank Blank

Elevated liver enzymes.

I am a 29 year old male, relatively active and such. I recently had blood work done to check cholesterol levels. The panel came back high. The numbers were 49 and 151 (not sure which was which). The morning before I had the blood work done I had not eaten or drank but I did take my Crestor, two Lortab 10mgs w/ 500 mg of APAP, Prinzide and a BC powder. Also, the day before I had one beer and three Lortab 10 mgs w/ 500 mg of APAP. I was wondering if these medications and the like were potentially the cause of the elevated liver enzymes? I have no abdominal pain or jaundice or any other symptoms. Thank you for your time.
Blank
Avatar_m_tn
Crestor is a statin and statins have been known to result in elevated liver enzymes. Often these elevations are not significant but they should be monitored regularly because it is possible to suffer liver damage if the enzymes are significantly elevated over a period of time. 151 - if that is your ALT or your AST is significant and  you should consult with your doctor as soon as possible.


".....Liver Enzyme Abnormalities and Monitoring

It is recommended that liver enzyme tests be performed before and at 12 weeks following both the initiation of therapy and any elevation of dose, and periodically (e.g., semiannually) thereafter.

Increases in serum transaminases [AST (SGOT) or ALT (SGPT)] have been reported with HMG-CoA reductase inhibitors, including CRESTOR. In most cases, the elevations were transient and resolved or improved on continued therapy or after a brief interruption in therapy. There were two cases of jaundice, for which a relationship to CRESTOR therapy could not be determined, which resolved after discontinuation of therapy. There were no cases of liver failure or irreversible liver disease in these trials.

In a pooled analysis of placebo-controlled trials, increases in serum transaminases to > 3 times the upper limit of normal occurred in 1.1% of patients taking CRESTOR versus 0.5% of patients treated with placebo....."

See:  http://www.rxlist.com/crestor-drug.htm


Good luck,
Mike
Related Discussions
Avatar_m_tn
Crestor is a statin and statins have been known to result in elevated liver enzymes. Often these elevations are not significant but they should be monitored regularly because it is possible to suffer liver damage if the enzymes are significantly elevated over a period of time. 151 - if that is your ALT or your AST is significant and  you should consult with your doctor as soon as possible.


".....Liver Enzyme Abnormalities and Monitoring

It is recommended that liver enzyme tests be performed before and at 12 weeks following both the initiation of therapy and any elevation of dose, and periodically (e.g., semiannually) thereafter.

Increases in serum transaminases [AST (SGOT) or ALT (SGPT)] have been reported with HMG-CoA reductase inhibitors, including CRESTOR. In most cases, the elevations were transient and resolved or improved on continued therapy or after a brief interruption in therapy. There were two cases of jaundice, for which a relationship to CRESTOR therapy could not be determined, which resolved after discontinuation of therapy. There were no cases of liver failure or irreversible liver disease in these trials.

In a pooled analysis of placebo-controlled trials, increases in serum transaminases to > 3 times the upper limit of normal occurred in 1.1% of patients taking CRESTOR versus 0.5% of patients treated with placebo....."

See:  http://www.rxlist.com/crestor-drug.htm


Good luck,
Mike
Blank
Post a Comment
To
Blank
Weight Tracker
Weight Tracker
Start Tracking Now
Liver Disorders Community Resources
RSS Expert Activity
469720_tn?1388149949
Blank
Abdominal Aortic Aneurysm-treatable... Blank
Oct 04 by Lee Kirksey, MDBlank
242532_tn?1269553979
Blank
The 3 Essentials to Ending Emotiona...
Sep 18 by Roger Gould, M.D.Blank
242532_tn?1269553979
Blank
Control Emotional Eating with this ...
Sep 04 by Roger Gould, M.D.Blank
Top Digestive Answerers
Avatar_m_tn
Blank
me_just34
317787_tn?1373214989
Blank
Dee1956
DC
1622896_tn?1418684976
Blank
bobdylan1958
Outside London, United Kingdom