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High ALT, AST, GGT levels - nothing else wrong in blood work
I recently had a blood/urine test for a life insurance policy.  Everything on the tests was good except for my liver enzyme levels.  My AST was 148, ALT was 294, and GGT was 70.  It's a mystery to me.  I do not drink alcohol and the blood work was negative for HIV, Hep C, and Hep B.  I have felt more tired in the last six months than normal, but nothing that has necessarily restricted my lifestyle.  I did have one fainting episode with a moderately strenuous workout at the gym.  Any ideas?
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Avatar universal
What has your doctor said?
The fact that your blood work, aside from these markers, is normal really isn't all that unusual. These number suggest a liver problem and perhaps your Bilirubin would be elevated but not necessarily.
There are autoimmune liver diseases - Autoimmune Hepatitis, Primary Biliary Cirrhosis and Primary Sclerosing Cholangitis. I certainly don't suggest that you have any of these but they do cause enzyme elevation.
Drugs can also cause elevations in liver enzymes - cholesterol medication, too much acetaminophen for instance and other drugs as well.
There is also Hemachromatosis (too much iron) and Wilson's Disease and other diseases that I can't think of or don't know about.
I do think that you should have follow up studies to determine the cause of your enzyme elevations. I would expect your physician to want to have further testing and  additional blood tests may rule out some of the possibilities.
Good luck,
Mike
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