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Avatar universal

High Liver Counts and Pain

My question is I have been having pain on my upper right abdomen since my pregnancy with my second child in 2006.  After my daughter was born in 11/2006 my liver counts were up so they did a hepatitus panel which came out to be negative did a CT scan which noted fatty liver.  Then they did endoscopy and colonoscopy but did not find anything abnormal except unusual amount of bile in my stomach and they did a biopsy but it burned up so could not be tested.  I had my gallbladder out in 1/06 after giving birth to my first child in 10/05 due to gallstones and cholegnitus? not sure of spelling.  Anyways they ran me through Echocardiagram then Stress test due to pain.  Then my family doctor said it was my back that was radiated to the abdominal pain.  I then went through MRI's of my neck and upper and lower back to find degenative and bulging discs not bad though never addressed.  Then a MRI of my sacrum do to swelling could not find anything said should do bone scan CT of pelvis which was done and showed some sacroillac changes cartriledge narrowing and mild ostes pubis.  Do to the pain I went to a neurologist because now I was having abdominal and severe back pain and could barely walk.  I am only 31 years old.  I ended up having nerve problems and had triple nerve decompression on both legs and then carpal tunnel on both hands.  I have to have another nerve test because the ulnar nerve seems to be problematic now.  Back to the liver problems the counts have been high every 6 months they are retested.  In 11/07 since they doubled I went to a Gastro. specialist which did a test to check for antigens found in autoimmune and PBC, etc.  it came back negative so said to wait 6 mo. to retest. I have a blood panel done 5/08 and the counts have gone up 5-6 times my ALT was 294 and my AST was 232 my protein was high at 8.6 and albumin at 5.4 %MONO 14 Hemoglobin 16.1.  They did a hepatitus panel and all negative.  I go back to my Gastro. spec. this Friday and I know they will do the same blood panel as was done in 11/07 I am just wondering if anyone has any suggestions or if a liver biopsy should be done?  The pain is constant and dull for the most part but lately it has been more severe and almost delibelitating at time.  Sorry for being so long I just wanted to give as much detail as possible.
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Avatar universal
Hi I'm new to the forum.  Just got over a mild case of pancreatitis.  Dr did a Hep Panel on me because liver emzymes have been high for a bout 6 months. Hep Panel came back non reactive. Now she wants to do Auto immune Hep panel on me.

Question is if Hep panel is fine why would she want to do Auto Immune Panel?

Also I have thyroid problems, Shogrens, arthritis.  If you have one Auto Immune Disease does usually mean you have others..

New at this please give me information.  Thanks
Helpful - 0
Avatar universal
Well I had the tests done the CT scan showed severe fat infiltration to the liver.  After having the EUS there was no gallstones in the ducts which they thought was the culprit.  I had a liver biopsy done 9/2 and they determined from that the changes were consistent with non-alcoholic steatohepatitis.  Does anyone have this and if so how did your doctor's go about this.  My gastro. just said we will wait and see and do blood test every 6 months not that I mind but if there is something I could do to help the process I would like to.  I appreciate any feedback you all can give.  
Helpful - 0
553516 tn?1255867219
I wish that they would do a liver biospy on me I have now had rasised liver function test for 6 months. Here in in england they just do blood tests and monitor you. It sounds a lot different in America
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Avatar universal
Hello everyone,  

Oh thank you for the feedback.  Not sure I understand the question of any overlap?  Well at my appointment they were concerned about the how high the LFT's came back.  I am now going for a CT scan of the abdomen and a EUS.  They want to check the ducts to see if anything is lodged there then after those results we will wait and see and if necesary a liver biopsy after that.  
Helpful - 0
Avatar universal
Hello,

I can't give you more advise as all of the members above have covered everything well. :o)
The only other thing I would like to mention is, PBC can show a false neg.. Do you know if you had any overlap?
Helpful - 0
Avatar universal
No I haven't had that procedure done.  Thank you for the information.  

I think I am going to go to my current Gastro. Friday to hear his opinion and if I am not satisfied.  I am going to go to Scripps in California as I am sure they see more complex cases then where I live.  

Thank you for your post.  
Helpful - 0
549269 tn?1236130637
Have you ever had an ERCP?  I was misdiagnosed with several things including autoimmune hepatitis and PBC.  I finally had and ERCP and it showed PSC, Primary sclerosing cholangitis.  I also have pain in the abdomen and some other health problems.

You should go see a hepatologist at a big hospital or university if possible.  Best of luck toyou!
Helpful - 0
Avatar universal
Thank you for your feedback and all your information that you have gone through.  I am hoping and praying for the best.  I have not had a biopsy yet.  For the past two years this has been the highest and it really jump from last November till the blood work done in May.  It has taken me almost two months to get an appointment to follow up about the blood work and I am going to really push for a biopsy.  I would rather be pro-active not reactive to whatever is going on with my body.  Thank you for letting me know on the gender I changed it I guess it automatically went to that when I set up my profile and I didn't look down to see that.  Take Care and thanks again!
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Avatar universal
Why does your profile show you as being a male?
Helpful - 0
Avatar universal
Except for the ALT and AST and biopsy.  I could have signed your  post.  I went through the same things beginning with  having a child at 27-  removal of gallbladdar, pain on side, back pain etc. I also had hypertension problems beginning then. So I was seeing a Dr. every six months and having blood work which was always normal. My alt and ast were normal 23 years. Then one night I had a nightterror , ran for help (I thought) hit a closed bathroom door and knowcked myself out thats when I ended up in hospital with a loss of memmory and unexplained high levels of ammonia in my blood. Had every test you had over 7 day stay. They found the degenerative disks osteoperosis ect. just like you. Then monitored my ammonia levels etc for six months couldn't find anything .  I saw a nerologist, gastrointerologist every  ( gist Dr.)  that was available. Finally decided to send me for a biop. Had one done they messed up did'nt get liver, only lymph node and colon. By then I was really scared so I insisted on getting another one 2 weeks . Bad news they don't know why because I don't have hep. don't drink or do drugs. But they told me I have Cryptogenic liver disease ( which is sort of like NASH or fatty liver (don't have fatty liver , never had a real bad weight issue. They tell me I have ESLD which had to have started many years ago. So I have had to go through the process of eveluation to get on the transplant list. I pray you don't have anything like that. By the way why did'nt you go for a bio.?  Take Care    

cat
Helpful - 0
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