Prograf is toxic to kidneys

Questions/Comments: Kidney failure after long-term use of Prograf (following Liver Transplant).

Following kidney failure, patient's newly transplanted kidney also began to slowly fail/decline (initially after transplant, while still on Prograf). However, the new kidney immediately began to recover after stopping the Prograf. Expert medical studies show that Prograf is toxic to the kidneys... Medical studies by experts at Albert Einstein Transplant Center support/promote the idea of stopping Prograf due to toxic effects on the kindey and using Cellcept (and Rapamune combo instead).

Additional Comments: In my opinion, Prograf should be taken off the market as soon as possible...as much better options are available (meds such as Cellcept and Rapamune that protect the kidney). I believe hundreds, if not thousands of other transplant patients are suffering untold harm due to Prograf. By 2003, the studies and experts have know of the issues with Prograf. What has been done in the interim to resolve the issues? Even today, Walter Reed transplant lists Prograf high on thier list of protocols, well above the Cellcept/Rapamune protocol. This is a travesty and needs to be corrected so that other patients do not continue to suffer from the use of the drug (Prograf) and the harmful effects on the kidney.

[mikesimon]

voice of experience.
Your conclusion seems a bit hasty and extreme to me.