"...Bilirubin levels can be used to identify liver damage/disease or to monitor the progression of jaundice. Increased total or unconjugated (indirect) bilirubin may be a result of hemolytic, sickle cell or pernicious anemias or a transfusion reaction. If conjugated(direct) bilirubin is elevated, there may be some kind of blockage of the liver or bile ducts, hepatitis, trauma to the liver, cirrhosis, a drug reaction, or long-term alcohol abuse...."
Gilbert's Syndrome is also a possibility when you have a normal direct bilirubin and an elevated indirect bilirubin. Gilbert's is a genetic disorder in which indirect bilirubin is elevated. It is considered to be a benign disorder and not a threat to the health of the patient.
In my opinion the bottom line is that an elevated direct bilirubin suggests a liver or bile duct disorder whereas an elevated indirect bilirubin suggests a non-liver issue.
Copyright 1994-2016 MedHelp International. All rights reserved.
MedHelp is a division of Aptus Health.
This site complies with the HONcode standard for trustworthy health information.
The Content on this Site is presented in a summary fashion, and is intended to be used for educational and entertainment purposes only. It is not intended to be and should not be interpreted as medical advice or a diagnosis of any health or fitness problem, condition or disease; or a recommendation for a specific test, doctor, care provider, procedure, treatment plan, product, or course of action. Med Help International, Inc. is not a medical or healthcare provider and your use of this Site does not create a doctor / patient relationship. We disclaim all responsibility for the professional qualifications and licensing of, and services provided by, any physician or other health providers posting on or otherwise referred to on this Site and/or any Third Party Site. Never disregard the medical advice of your physician or health professional, or delay in seeking such advice, because of something you read on this Site. We offer this Site AS IS and without any warranties. By using this Site you agree to the following Terms and Conditions. If you think you may have a medical emergency, call your physician or 911 immediately.