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antibiotics
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antibiotics

Can anyone tell me if Levoquin or erythromycin are safe to take for a cirrhotic person who has a sinus infection.  They are allergic to Sulfa and PCN.  Any help would be appreciated!
Avatar dr f tn
Hello and hope you are doing well.

Am quoting two studies below:

Pharmacokinetic studies in hepatically impaired patients have not been conducted. Due to the limited extent of levofloxacin metabolism, the pharmacokinetics of levofloxacin are not expected to be affected by hepatic impairment .

In the presence of normal hepatic function erythromycin is concentrated in the liver and is excreted in the bile; the effect of hepatic dysfunction on biliary excretion of erythromycin is not known.

So, the status is not known, but regular liver function tests will help to monitor.

Hope this helped and do keep us posted.
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