can anitbotoics affect the liver

I have a lot of liver funtions tests that keep coming back adnormal. Can taking really strong anitbotoics affect the liver. I have to take them becaause I have a biscupid Aortic valve..I got bit by a dog last last week. I cant have any infections going on to the valve.

[aMom21]

From what I read some antibiotics can affect the liver but I am not exactly sure how.

[CCRN34]

Yes, there are antibiotics that can potentially be toxic to the liver.

[birdlady50]

do you know which anitbotiocs they are
thanks

[KjFlicka]

from cpmc.org....

Following is a list of hepatotoxic drugs. Patients who take these medications (regularly or daily) should undergo monthly laboratory testing for the first three months of therapy and then every three to six months because of the association between these medications and liver disease.

acetominophen, particularly hazardous when taken with alcohol or anti-seizure medications
alpha-methyldopa (Aldomet)
amiodarone
carbamazapine
chlorzoxazone, Parfon-forte
dantrolene
diclofenac, voltaren
fluconazole or ketoconazole
flutamide
hydralazine
ibuprofen
imuran/azathioprine/6-MP
isoniazid (INH)
Ketek
long-acting nicotinic acid
luekotriene synthase inhibitors (asthma medications) [Zafirlukast Accolate] and zileuton (Zyflo)
methotrexate
nitrofurantoin (Macrodantin)
perihexilene maleate
phenylbutazone
phenytoin
pravastatin, fluvastatin, simavastatin, lovastatin,
quinidine
rifampin
sulfa medications (especially Septra or Bactrim)
tacrine
Tasmar (tolcapone) [Parkinson's Disease]
Ticlid
troglitzone (Rezulin)
vitamin A (in doses greater than 5,000 Units/d; beta carotene is safe at all doses)

According to the April 1996 New England Journal of Medicine, the most common cause of acute liver failure in the United States is the negative interaction between acetaminophen (Tylenol) and alcohol. In addition, there are interactions that are less common but equally as serious. Research suggests individual genetic variations in liver enzymes may be the cause.



Hope this helps!!

[birdlady50]

Many many thanks for the info. I on  simstattion any way and (beater blocker. and warfin Heart drugs)