Aa
Aa
A
A
A
Close
Avatar universal

my results / worried about autoimmune hepititis

need advise on these test results, my results were:

neg for all hep viruses
anti nuclear antibodies -negative
mitochondrial antibodies positive ( shows weak antibodies present,pattern unclear)

mitochondrial titre 40
smooth muscle  - positive, very weak smooth muscle (non-actin) antibodies. ( was later tested a few weeks and shows negative, abnormal results blamed on a viral cause)
antibodies
smooth muscle Abs titre - 40
ast 45
alt 46
total bilirubin 15
total protien 84

i find that when i exercise and diet my ALT drops alot almost comming back to normal, do the above results show i may have autoimmune hepatitis? or does it simply seem a more of a diet and health issue, i have taken out sugars and wheat form my diet have lost weight, but i wasnt much overwieght, i have done this as i have got high cholestrol,
it was at 6.8 now ha gone to 6.2 and seems to be dropping because of change of diet and exercise.

the ALT hangs around 80's and 90's normally but after i have started exercising and losing weight which i have, it has come down to  40's, is this typical in autoimmune hepititis? so far i have been shown that exercise and diet cannot really slow autoimmune hepititis apart from it being a good and healthy thing to do, so in this case if it was autoimune
hepititis the ALT would not drop because fo my change to a healthier lifestyle?

also i am worried about the mitochondrial antibodies as nothing has been done after this tested positive, shouldn't the drs have a further investigation on this?

thank you
3 Responses
Sort by: Helpful Oldest Newest
Avatar universal
wq2
Anti-LKM test for type 2 autoimmune hepatitis, apparently there are two kinds of this disease.
Helpful - 0
Avatar universal
hi thanks for the reply,  i did post the same thing else where too, thanks for that reply too, you have been very helpfull, i was tested negative for ANA, smooth muscle was positive but now tested neg, i have not had the anti-LKM test, what would this look into?

its odd the notes show its weak AMA and pattern unclear, i also have a history of suspected prostratitis for many years and i will be seeing a urologist in a few weeks,

i will phone for a hepatology or a gastroentologist appointment tomorrow,
what are the best tests to do next for a further diagnostic, i have also been diagnosed with fatty liver ( i was a social drinker i have totally stopped) so this will not be helping if i also have pbc. i will work hard on losing weight and keeping fit, i also am taking vit d and calcium as my bones were hurting alot and feel very weak, feel lethargic,tired all the time,

i was refered to a hepatologist but he assumed that it was the fatty liver causing the raised alt, i told him thefatty livers recent but he didnt believe me, so will go to a gastroentologist, what tests do you recommend for autoimmune hep and pbc to do next apart from livrer biopsy?

many thanks
Helpful - 0
Avatar universal
wq2
Did you also  get tested for  antinuclear antibodies (ANA)  and antibodies to liver and kidney microsomes (anti-LKM)?

If I am not mistaken - REMEMBER NOT A DOC, JUST ANOTHER PATIENT HERE -  the antimitochondrial antibodies (AMA) test is for primary biliary cirrhosis.

High ALT levels caused by liver disease usually drop when the cause of the disease is removed or has been severely weakened.

Did you get a GI appointment?

Good luck
Helpful - 0
Have an Answer?

You are reading content posted in the Liver Disorders Community

Didn't find the answer you were looking for?
Ask a question
Popular Resources
Learn which OTC medications can help relieve your digestive troubles.
Is a gluten-free diet right for you?
Discover common causes of and remedies for heartburn.
This common yet mysterious bowel condition plagues millions of Americans
Don't get burned again. Banish nighttime heartburn with these quick tips
Get answers to your top questions about this pervasive digestive problem