please please could explain my liver biopsy results!!!

[bournemouth]

could please explain my liver biopsy results and explain more what they mean by small foci of pericellular fibrosis, is that can be treated????

my liver biopsy results as follow:

needle cores oh hepatic tissue show marked steatosis (grade 3).
occasional mallory bodies are seen. there are small foci of pericellular fibrosis. no evidence of cirrhosis is seen.
the appearance are of a low grade steatohepatitis.
the differential diagnosis(if alcohol has been excluded) includes diabetes mellitus, obesity and drug reaction ? lansoprazole
discussion at an MDT might be helpful

please could anyone explain to me exactly what does the results mean and what do you suggest the treatments?
is fibrosis can be treated or not

patien history:
I am 25 years old, I have evaluated alt between 120-240
I have done ultrasound the result was as follow:
technically difficult scan due to patien body habitus.
the liver is normal in size and contour. the echogenicity of the liver increased consistent with fatty infiltration.
the posterior aspects of the liver are poorly visualised due to loss of through transmation. situated with the region of the gallbladder fossa are 2 echo poor areas the largest measures 9mm in diameter. appearances are likely to represent area of facal fatty sparing.
pancreas  normal, the spleen, gallbladder, biliary tree appear grossly normal

thank you for help

[HectorSF]

Steatosis, also known as fatty infiltrates in the liver or Fatty Liver, a condition characterized by the accumulation of fat in the liver, and it is commonly seen in people infected with the hepatitis C virus (HCV). It is estimated that about 55% of HCV positive individuals have steatosis, which is two to three times the prevalence seen in the general population. Studies have found that the combination of hepatitis C and steatosis increases the risk of HCV disease progression, reduces the likelihood of responding to HCV treatment, and may contribute to the development of liver cancer (hepatocellular carcinoma, or HCC).

Do you have Hep C?

Talk to your medical doctor (Gastroenterologist) about a diet and exercise program that will help to reduce steatosis. Unfortunately, there are no medications at this time to treat steatosis. However, there are strategies to help reduce steatosis in people with hepatitis C and to lessen the impact of steatosis on HCV disease progression and treatment outcome. It appears that diet, exercise, and maintaining a healthy weight are important strategies to help reduce and possibly eliminate steatosis.

Best of luck.

HectorSF

[Niknak1974]

I am not a doctor, so this is only something I recall from a similar test results.  It sounds like they couldn't get a clear enough picture due to being overweight (I had the same on my ultrasound - which made me question the use of the ultrasound in overweight people), and that there is evidence of fatty liver disease, which is common in overweight people or those that drink heavily, and or take medications that can affect liver.  They should tell you that you may need to change your eating habits and stop any intake of alcohol, as well as limit your use of Tylenol.  I got a similar diagnosis and spoke to the doctor about seeing a dietician.  I was also told that as long as it is in this state (not cirrhosis) it is reversable through diet and also exercise.  Just remember that I am not a doctor, and there are definitely good reasons to go see your doctor and get him/her to explaint he diagnosis to you.

good luck.