cheer mike
yeah i think i read that report so its a sign of insulin resistance because it happened to me i had abnormal ALT levels for over 8 years also have got fatty livr recently been a year with it. i started taking vit e and it has lowered the ALT to normal levels the drs are shocke but dint know why. even though i explained i started taking vit e.
this is a sign for me to becoe healthy before its too late
thanks mike
"Nonalcoholic steatohepatitis (NASH) is a hepatic disorder associated with the metabolic syndrome and insulin resistance. It is a very common problem for which no therapy, short of diet/weight loss and exercise, has shown benefit. Extreme measures of weight loss include bariatric surgery, which has not been well studied, but may be beneficial.[1] Accordingly, there is considerable interest in developing pharmacologic therapies directed toward addressing the presence of insulin resistance. There is also interest in exploring the effectiveness of antioxidant therapy because of the role oxidant stress plays in the development of NASH...."
".....The results showed that use of vitamin E was beneficial in ameliorating several parameters of disease progression. Improvement in NASH, as measured by using a composite of standardized scores for steatosis, lobular inflammation, hepatocellular ballooning, and fibrosis, was observed in 43% of patients receiving vitamin E compared with 19% of patients receiving placebo (P = .001). Specific improvements conferred by vitamin E in comparison with placebo included significant reductions in serum alanine aminotransferase (ALT)/aspartate aminotransferase (AST) (P < .001), hepatic steatosis (P = .005), lobular inflammation (P = .02), and hepatocellular ballooning (P = .01). No significant improvements in fibrosis scores were observed with use of vitamin E...."
See Clinical Care Options: http://tinyurl.com/24kny9j
"May 4, 2010 — Supplementation with the natural form of vitamin E (800 IU/day) has beneficial effects in patients with nonalcoholic steatohepatitis (NASH), but pioglitazone's benefits are less clear, according to the latest findings from the Pioglitazone vs Vitamin E vs Placebo for the Treatment of Nondiabetic Patients with Nonalcoholic Steatohepatitis (PIVENS) trial, reported online April 28 in the New England Journal of Medicine......."
See: http://www.medscape.com/viewarticle/721221?sssdmh=dm1.615392&src=nldne&uac=39980BG
I hope this helps.
Good luck,
Mike