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Liver Transplant  (Expert Forum)
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Acetaminophen overdose three years ago resulting in liver problems now??
Answered by
Thomas D Schiano, MD - Internal Medicine, Gastroenterology, Liver Transplantation, Hepatology
The Mount Sinai Medical Center New York - NY
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Questions posted in the Liver Transplant . Forum are answered by medical professionals from The Mount Sinai Medical Center.

Acetaminophen overdose three years ago resulting in liver problems now??

by caecae, Mar 17, 2009 02:30AM
Hi,

I'm not sure if this is the right place to post this but wasn't sure where else to.  About three years ago, when he was 20, my brother took an overdose of Tylenol ("a bottle" is what he told me; I have no idea what dosage or how many) while drunk, with suicidal intent.  The next day, he was sick to his stomach, but within another day, he was fine.  I am the only person in our family who knows about this.

Today, my mom told me that there is "something going on with his blood."  He was having joint pain and went to see a doctor who thought it may be Lyme disease.  But after blood tests, it turns out that this is not the case.  The blood tests indicated that his red blood cell and bone marrow count are abnormally low, but "not low enough to indicate leukemia."  

He's going to see a hematologist next week, but I'm really worried now.  Does his low red blood cell/bone marrow count sound like it could be related to a liver problem?  Is it possible for an Acetaminophen overdose three years ago to result in liver failure now?  My brother also drinks quite regularly.

Thank you so much.  

by Thomas D Schiano, MD, Mar 18, 2009 06:51AM
the tylenol OD several years ago has nothing at all to do with what is going on now.  It is conceivable that the low counts are due to a liver condition affecting the bone marrow or by causing an enlarged spleen.  significant alcohol use could do both.
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