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Itching and liver engimes are high after 1.5year of liver transplant
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Itching and liver engimes are high after 1.5year of liver transplant

Dear Sir,
   I am 37 year old. I under gone liver transplant in july 2011, Since last december,2012 I have itching and liver engime gone high(SGOT-453,SGPT-300,GGTP-1050,AlkalinePh-300,Bilirubin-2.32). The DNA test shows negative and AntiHBs-94. Yesterday MRCP has been done. Seeing the result doctor says bile duct obstruction is not the reason. I asked where the rejection is the cause or not. He says since my sister donated liver, chance of rejection is less. The Tac level  is 6.8ug/L. In between ursocol 300mg(BD) was given for 2weeks and ciplox 300mg was given for 1 week. But engimes did not comeback. Infact after stopping of Ursocol the engimes went further high.
According to you what could be the reason? And what are the possible solutions?
517301_tn?1229801385
with the enzymes this high, rejection has to be a consideration.  I would unequivocally get a liver biopsy to rule out rejection.  it is not true that recipients of live donors have lower incidences of rejection
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517301_tn?1229801385
Thomas D Schiano, MDBlank
The Mount Sinai Medical Center
New York, NY
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