Immediately below is an excerpted statement that I frankly found surprising. Any comments or feedback welcome - thank you!!
Quoting the Merck Manual:
"Clinical signs that suggest a chronic liver disorder or chronic alcohol use but ARE NOT SPECIFIC FOR CIRRHOSIS** include muscle wasting, palmar erythema, parotid gland enlargement, white nails, clubbing, Dupuytren's contracture, spider angiomas (< 10 may be normal), gynecomastia, axillary hair loss, testicular atrophy, and peripheral neuropathy."
** emphasis added. This statement seems to suggest that one could be presenting with any or all of these symptoms - and yet still not be cirrhotic. Presumably it's saying that F3 status...a seriously damaged/fibrotic liver that's not yet cirrhotic...could present with any or all of these symptoms.
My question is twofold:
(a) Is the above an accurate statement? Do you have a differing interpretation... and/or remarks?
(b) What is the likelihood of frank cirrhosis in a mildly anemic patient with all normal LTFs and a platelet count of 271,000? Does such a 'fully normal' platelet count necessarily preclude frank cirrhosis?
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