I have two questions about partial liver transplants:
1) Is there a "threshold" MELD score at which partial transplants are not performed? What is makes a good candidate for a partial transplant?
2) Are there statistics as far as the mortality rate for donors and or general risk information? Can donors live normal lives afterward, or are they restricted in any way? (including becoming pregnant etc).
we cite a mortality rate of about 1-2% for the procedure. You can check the literature from the A2ALL study group that has complied a lot of information on this. Adult patients should not be too sick to receive a live donor--in NY the threshold is not to do it above MELD 25. We expect donors should have a mormal life and now have data for about 10 years. someone who is healthy, the same blood type and the same size or larger than the recipient may be a good candidate.
I will tell you as a liver donor to my husband, i am perfectly fine except the big mercedes scar in my stomach, however doctor advice if I want to get pregnant,,maybe wait for a little bit maybe a year or two to be safe. i am perfectly fine thank God.
you can ask me anytime for some info and my experience.
I am surprised by the low numbers of surgeries each year (looks like 350 or so) despite the 15,000 + awaiting transplants. I understand everyone on the list is not in critical condition, but I'd expect a larger number of partial transplants. Is there a reason the numbers haven't grown?
Is it because of the nature of the surgery itself and the risks involved?
yes. the donor has potential riosks. in addition, in parts of the country there is an inequity on the waiting list. in NY, patients need MELD scores of 30 to get transplanted while in the midwest and south it may be closer to 20. thus, live donor liver transplants are not needed in certianm parts of the country. In addition, only about 20% of recipients have potential suitable donors.
My sister continues to tell me about a partial transplant and like for me to be the donor. I have not however found much info on effectiveness. I will share that she is an alcoholic and has to have fluids drained regularly therefore may not be a candidate. Can you tell me how safe it is for me and for her and if this is something that we may want to check into.
For a guide to the Living Donor process see:
It is a good overview of the entire process and explains the benefits for the recipient and risks to the donor. It describes the entire process (select "Information guide for potential live liver donors" )
Also read "FAQ" on same site.
To Babyblueyes910, This is major surgery for the donor, unless the recipient has demonstrated clear ability to stay off alcohol and is likely to remain off it after the transplant, I would be hesitant about it.
The Content on this Site is presented in a summary fashion, and is intended to be used for educational and entertainment purposes only. It is not intended to be and should not be interpreted as medical advice or a diagnosis of any health or fitness problem, condition or disease; or a recommendation for a specific test, doctor, care provider, procedure, treatment plan, product, or course of action. Med Help International, Inc. is not a medical or healthcare provider and your use of this Site does not create a doctor / patient relationship. We disclaim all responsibility for the professional qualifications and licensing of, and services provided by, any physician or other health providers posting on or otherwise referred to on this Site and/or any Third Party Site. Never disregard the medical advice of your physician or health professional, or delay in seeking such advice, because of something you read on this Site. We offer this Site AS IS and without any warranties. By using this Site you agree to the following Terms and Conditions. If you think you may have a medical emergency, call your physician or 911 immediately.