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Liver Transplant  (Expert Forum)
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Vagus Nerve Damage
Answered by
Thomas D Schiano, MD - Internal Medicine, Gastroenterology, Liver Transplantation, Hepatology
The Mount Sinai Medical Center New York - NY
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Questions posted in the Liver Transplant . Forum are answered by medical professionals from The Mount Sinai Medical Center.

Vagus Nerve Damage

by liverbelching, Aug 12, 2009 09:43PM
I have a thought I'd like to bring up here and get your opinions on.  I know that the invasive nature of liver transplant leads to the possibility of unforeseen surgical effects.  I myself have never had a transplant, but have had something that (like a transplant) might have damaged some of the viscera surrounding the liver - namely, a liver biopsy (stage 3 bridging fibrosis)

So, here are my symtpoms:
-Uncontrolled belching (nothing I do would cause aerophagia).  Seems triggered by movement and whenever my stomach is full (standing up, sitting down, etc.,)
-Intermittent pain in my right side.  It varies quite a bit in intensity, but never hits what I would consider "gallstone level".  Usually after eating, but not always
-Dizziness (have passed out when standing up several times).  I drink at least 70-100 ounces of liquid a day.
-"Normal" other liver symptoms (occasional itching, fatigue, bleeding into skin)

So, is it possible that my vagus nerve was damaged in the liver biopsy?

Vagus Nerve -> causes GB contraction -> mild/intense RUQ pain
Vagus Nerve -> causes diaphragm movement -> belching
Vagus Nerve -> parasymphathetic to autonomic nervous system -> low heart rate/pulse -> low blood pressure -> orthostatic hypotension

As a slight confirmation, when I had an ultrasound, my GB was contracted despite my not having eating for past 10 hours.

Also had a upper endoscopy which showed nothing

Or is it possible the scar tissue in my liver is bumping up against something and causing these symptoms?

by Thomas D Schiano, MD, Aug 13, 2009 05:38PM
I CANNOT EXPLAIN YOUR SYMPTOMS BUT REALLY FEEL THAT THE BIOPSY NOR YOUR LIVER CONDITION ARE PLAYING A ROLE HERE.
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