My son (9 yrs now) went thrrough Liver Transplant on June 3rd, 2008. He was CMV positive 3 months post transplant and his biopsy was done and no abnormality was found. Now doctor says that it is mandatory to go for biopsy again 1 year post transplant.Could you please tell me if it is really necessary, all his liver tests are normal like alt and ast are 29 and 19 respectively and normal since last 4 months. Only globulin is fluctuating between 4.5 and 5gm/dl( normal range is between 1.8 - 3.6) .Also his IgG is elvated 2300 mg/de ( normal range between 650-1600). Also he is recently detected EBV positive.
Please let me know if biopsy at this stage is required and it is a general practice to get biopsy after one year post transplant. Also will it give some guidelines to treat EBV positive and elevated IgG and Globilin
this sounds like a protocol biopsy but frankly its not unreasonable in the pediatric setting because of the EBV issue and some times a chronic hepatitis can develop and smolder and cause significant liver damage over time. an elevated IgG might be seen in this setting.
The Content on this Site is presented in a summary fashion, and is intended to be used for educational and entertainment purposes only. It is not intended to be and should not be interpreted as medical advice or a diagnosis of any health or fitness problem, condition or disease; or a recommendation for a specific test, doctor, care provider, procedure, treatment plan, product, or course of action. MedHelp is not a medical or healthcare provider and your use of this Site does not create a doctor / patient relationship. We disclaim all responsibility for the professional qualifications and licensing of, and services provided by, any physician or other health providers posting on or otherwise referred to on this Site and/or any Third Party Site. Never disregard the medical advice of your physician or health professional, or delay in seeking such advice, because of something you read on this Site. We offer this Site AS IS and without any warranties. By using this Site you agree to the following Terms and Conditions. If you think you may have a medical emergency, call your physician or 911 immediately.