PET scan positve vs biopsy negative

My brother 60 yr old with an on and off history of smoking. His PET scan for postive for 1 nodule (2.1cm) in the right middle lobe and the biopsy is negative for cancer. What direction do you go to confirm one or the other?

[Dr Santos]

Hi,
How is your brother? Lung nodules  or small masses of tissue in the lung are common and are usually benign.  It is good that the the biopsy result was negative.  Monitoring of the nodule for any change in size, shape or appearance is usually done with this finding. It is best that you discuss the results with his doctor for proper evaluation. Factors such as your brother's medical history, presence of symptoms and results of other diagnostic tests and physical examination are important considerations also. Take care and best regards.