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autoimmune

my ana tests was 1160 and neg. for rhemitoid factor, what does all of this mean?
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Hi!
Generally a high ANA titre indicates an autoimmune disease (SLE, Sjögren's syndrome, rheumatoid arthritis, autoimmune hepatitis, scleroderma, polymyositis, autoimmune hemolytic anemia, dermatomyositis, primary biliary cirrhosis, Addison disease, Idiopathic thrombocytopenic purpura (ITP), Hashimoto's Thyroiditis, and type 1 diabetes mellitus). Mixed connective tissue disorders also cause a high ANA. What is important is the pattern of ANA staining: homogenous, speckled, or nucleolar.
Depending on the pattern of ANA staining, other antibody tests will have to be done. The pattern of staining itself is quite diagnostic (for eg in SLE a homogenous pattern is seen, nucleolar pattern in scleroderma and speckled pattern in ITP and mixed connective tissue disorder and in lupus). Do discuss this with your doctor. Take care!
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