I will make this as simple and short as possible....
1999 I had a positive ANA at 1:80 speckled and a positive anti DNA of 3.7 (anything over 3.5 was highly indicative of SLE)
normal c3 c4
neg sed rate & negative RFactor, normal CRP
I have pernicious anemia
in 2005 was dx with hashimotos
fast forward to today 2013
positive ANA 1:320 speckled
NEGATIVE anti DNA
C4 elevated at 0.59 range is 0.10-0.50
CK muscle elevated at 270 normal is <200
NEGATIVE extractable nuclear antibodies
TSH LOW at 0.26 range is 0.27-4.2 while on 175 mg of synthroid and 25mg of cytomel
LOW vitamin D at 60 range is 75-150
MCV 81 range 82-98
MCH 26.7 range 27.5-33.5
RDW 15.3% range 11.5-14.5
All of this autoimmune stuff is tricky. Just when they think they have it figured out, the lab work changes.
This is what I know. It takes more than labs to get a dx of lupus. You have to have some symptoms too. The speckled pattern is seen in SLE, and numerous other autoimmune diseases and in some healthy individuals who have a low amount.
Anti-DNA is VERY specific to lupus. Less than 1% of healthy individuals have a positive DNA. It usually indicates kidney involvement. So a neg. doesn't mean you don't have lupus. It just means the activity has slowed down. So you or the dr. shouldn't be looking at that as a basis of whether you have the disease or not. You also mentioned pernicious anemia. That too is one of the 11 criteria. So right there you have 3 out of the needed 4 for a dx. Many times, autoimmune diseases travel in multiples. So it's not uncommon for someone with lupus to also have another like Hashimoto thyroiditis.
You listed these symptoms:
symptoms are fatigue, hair loss, stiff joints, mood swings, irregular menstruation....
Does you joints ever swell?
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