What else causes low CD57?

[Todd36]

it seems like there are a lot of people with questions related to CD57.  It would be nice to have a doctor give an overview of the marker, eh?

anyway, i got my CD57 back today and I clocked in at 40 but I'm still waiting on western blot.  My dr said that it wasn't that low but it was lower than average.  The scientific literature says 60-360 is the normal range.  My white blood cell count is normal, EMG and NCS are normal, brain and C-spine MRI normal, and neurological exams are normal, but I'm still dealing with strange, diffuse pain and muscle twitching with the recent development of eye and throat pressure.

Besides lyme disease, what else does a low CD57 point to?  I know it can be low for HIV but that's out of the quesiton for me as I've been married for 10, and I had an HIV test before I was married and I haven't have blood transfusion.  SO...what else does a supressed CD57 indicate?  High CD57 is indicative of cancer, but low????

your input is appreciated.

Thanks,
Todd

[abravar]

hi there, i have no chronic lime decease and i tested CD57 "95"  and "44" this year

[RobNOrl]

I also have parvovirus, which is what you may need further treatment for.

[Ephedra]

I would think so.

[RobNOrl]

Just wanted to see if anyone knows if parvovirus, cytomegalovirus, and HHV6 could cause low CD57 counts. Mine is at 59 after only two years of Lyme.

[RobNOrl]

Your cd57 count should only go below 60 if you have chronic Lyme. The fact that it even gets that low probably means there are multiple co-infections and deficiency present.Band 23 on the IgM is very specific to Lyme, and is the only band I tested positive with, and my Lyme specialist has said he is sure I have Lyme Disease. I also was originally diagnosed immediately when my other doctor saw the erythema migrans or bull's eye rash two years ago. It still comes back in the same spot from time to time. He says 1 out of 6  ticks in the state of Florida are now carrying it. I'm wondering if Band 23 is specific to a particular strain here in Florida. Makes sense, since the birds migrate south every winter. There's only one other type of rash that resembles the Lyme bull's eye, and that's from STARI, or Southern Tick   Associated Rash Illness, which carries most of the same symptoms as Lyme, only usually is not as severe. However, Lyme is not as severe in warmer weather, so I think doctors may have made up a new name for Lyme in the south, since originally it was denied that you could catch it outside of New England.

[Ephedra]

The CD57 count is not diagnostic of Lyme by any means!  Things change, especially with Lyme.  You need to find an ILADS trained physician.  Not a Lyme doctor or a Lyme specialist, a Lyme Literate Medical Doctor trained by ILADS.  They know how to work with the testing and Borriella to improve your chances of getting a positive result.

Was this an IGenex western blot?