MTHFR is the scientific name for Methylenetetrahydrofolate reductase. It is also the gene that provides the body with instructions on how to make an enzyme called methylenetetrahydrofolate reductase. When one has a genetic mutation involving MTHFR, they have something called a variant of that gene. There are 24 known variants to the mutation and they can cause no problem at all or have very serious health complications. There is a lot of debate and confusion regarding this genetic mutation and as a result a whole lot of medical studies on the topic.
The following are a few of the more reliable sites regarding MTHFR and it's role in pregnancy (or loss of):
And lastly a very medical text and specific genetic information with respect to MTHFR: http://www.genecards.org/cgi-bin/carddisp.pl?gene=MTHFR
Undoubtedly you will find a lot of other information regarding MTHFR out there on the World Wide Web, but what counts is what your physician or specialist believes is going to be helpful for you. Each person is affected by MTHFR differently. A person can have a single copy of a mutation (Heterozygous) or both copies of a mutation (Homozygous). A person can even have more than one mutation with a single or double copy called Compound Heterozygous/Homozygous and it is important to note that each variation of the mutation does or can affect each person differently or even not at all - which is likely why there is much dispute about it in the medical community.
I hope if you have information that you have found that you will share it with others here, along with your journey.
In addition to anything I have mentioned, please keep in mind, that while I or others may have extensive knowledge in many areas, you should always seek professional medical advice from your own physician, as it pertains to medical conditions or concerns.
Good luck, and if you have any other questions that I can help you with, please feel free to message me directly.
Sincerely, Sandi (Dragon1973) MedHelp Genetics Community Leader; Children - Special Needs Community Leader; Down syndrome Community Leader & Ds Group Forum Founder/Moderator; MTHFR Group Forum Founder/Moderator
This site complies with the HONcode standard for trustworthy health information.
The Content on this Site is presented in a summary fashion, and is intended to be used for educational and entertainment purposes only. It is not intended to be and should not be interpreted as medical advice or a diagnosis of any health or fitness problem, condition or disease; or a recommendation for a specific test, doctor, care provider, procedure, treatment plan, product, or course of action. Med Help International, Inc. is not a medical or healthcare provider and your use of this Site does not create a doctor / patient relationship. We disclaim all responsibility for the professional qualifications and licensing of, and services provided by, any physician or other health providers posting on or otherwise referred to on this Site and/or any Third Party Site. Never disregard the medical advice of your physician or health professional, or delay in seeking such advice, because of something you read on this Site. We offer this Site AS IS and without any warranties. By using this Site you agree to the following Terms and Conditions. If you think you may have a medical emergency, call your physician or 911 immediately.