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MFTHR or is MFTHR Mutation - Blood Clotting

by Berko, May 26, 2006 12:00AM
After having my second m/c in March my dr. decided to test me and my husband to see if we could find out why m/c. the tests have finally all come in and the one that came out positive was mine for MFTHR (MFTHR? - not sure of the exact letters). my dr. saidit's a genetic disorder that makes people who have it more prone to bloodclotting and complicates pregnancy causing the blood to clot and therefore the oxygen doesn't get to the baby and usually results in early pregnancy loss. He gave me prescriptions for extra folic acid, vitamin b6, and baby aspirin in addition to my regular prenatal. i'm relieved that the problem is something that seems can be easily resolved (G-d Willing). he says he'll also give me heparin shots to keep blood thin once pregnant. i know i've read in past posts people who've had blood clotting and that they've been treated, but i wanted to see if i could get any feedback on any one who's had this and carried healthy pregnancy to term. my dr. didn't seem worried so i'm not really, but it's always good to hear other people's experiences with it. feel free though to use this also for any other questions or comments. thanks.
Member Comments (5)

by Berko, May 26, 2006 12:00AM
i just realized i wrote MFTHR twice when i meant to write maybe it's MFHTR - now i'd guess it's MFTHR if i keep writing it like that - that's what's stuck in my head.

by diamondtracy, May 26, 2006 12:00AM
I'm not sure about your particular disorder, but i can give you my experience . I have a blood clotting problem as well, it was found when I was 6 months pregnant during my first pregnancy.(my son is now almost 2). they found several small clots in my legs and a very large D.V.T.; they also said that my lupas anticoagulant was positive , which means that i am more prone to future clots and P.E. I was put on heparin injections twice a day until  after my son was born;(then I was switched to coumadin) My labour had to be induced early so it could be monitored properly, I wasn't able to have an epideral; and I wasn't able to breast feed.It was very stressfull having to going to the hospital every other day to have my blood checked, but it the end it was all worth it; my son came out 2 weeks early,and a  perfectly healthy 7 lbs 11 oz. We are now trying for our second through IUI(just like the first) so I had to get back on the injections because the coumadin is very dangerous when pregnant, I know if and when we do concieve it will be a long nine months of blood checking and shots, but I can't wait!  Sorry I rambled on a little but i hope i was of some help. I wish you all the best :)

by justsomegirly, May 26, 2006 12:00AM
To: Berko
I'm not sure what your post was about but I just wanted to say hello :) (i hadn't seen you post anything in a while). I hope everything goes well.

by Berko, May 30, 2006 12:00AM
To: diamondtracy; justsomegirly
diamondtracy: thanks for your response. i don't know if what i have is exactly the same as yours - my dr. didn't seem to think i'd have a problem with blood clots other than the ones that can cause early pregnancy loss - that the oxygen can't get to the baby and therefore pregnancy. he did say he'll start me on heparin shots when i am next pregnant (G-d Willing). I think with what i have the pregnancy wouldn't even get to 6 months, but thank you for sharing your experience with me i now know what else i'd like to ask the dr. - if i should be worried about any of the problems you mentioned. enjoy your 2 year old - i hear it's the best age - lots of fun chasing them around - huh?!!?

justsomegirly: hi. thanks so much for the hello - hope all is well with you. i'm just glad that we now know what the problem is and it's easily treatable. i'm looking forward to trying again and hopefully the next one sticking and being healthy!!!

by amezquitadetepic, Sep 29, 2009 10:07PM
To: berko
I have MFTHR genetic mutation as well,  I have had 1 pregnancy, with no m/c (fortunately), however, this is b/c I was diagnosed as a child (resulting in my first DVT at 14 y/o).  I was place on Lovenox shots (Low molecular weight heparin) along with folic acid, calcium, baby aspirin, as well in addition to my regular prenatal vitamin (this was taken during pregnancy planning, and through my pregnancy).  These vitamins are taken due to a vitamin malabsorption cause by MFTHR (i believe), also a good amount of Calcium is lost during normal pregnancy as well (i was taking 1000 mg of CA/day and my tooth still chipped off).  These vitamins are also vital to the fetal development.  I had to be induced 2 weeks before my due date b/c it MUST be a PLANNED pregnancy.  This is because Lovenox takes 24 hrs to leave the body's system, and most induced labors that early result in c-sections.  (which mine did as well)  One must be prepared for pregnancy and labor b/c there are many risks (including placental clotting, and/or hemorraging)  My c-section resulted in a uterine hematoma, which healed just fine.  A NORMAL LIFE MAY BE LIVED WITH THE MFTHR GENETIC MUTATION; however, one must take good care of his/her health.

THank you,

For more questions regarding the MFTHR mutation/DVTs, please feel free to contact me,  ***@**** subject it with MFTHR / DVT so that it does get deleted automatically...
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