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Progesterone suppositories...when did side effects start...if any at all??

by babytee, Nov 06, 2006 12:00AM
I'm 5 weeks preggo today and I started spotting last week when I went to the doctor (11/1) so due to a prior m/c, she put me on progesterone suppositories- 100mg once at bedtime. She said they might make me feel icky but so far I've been okay other than the sore bbs that started yesterday. Just curious if these were my normal symptoms of pregnancy or is it a late side effect of the progesterone?  Any experience??
Member Comments (22)

by thendricks, Nov 06, 2006 12:00AM
I had to take them too, I started the same time as you, Make sure to wear a mini-pad, I had to take 200mg at 1 time yuck, they made me agitated, cranky and kinda depressed really also they increase your pregnancy symptoms so I was told, my breast were really sore and I always felt sick to my tummy but I never actually threw up, God bless and congrats

by Allie1980, Nov 06, 2006 12:00AM
Baby Tee--

I also have had a miscarriage and am going to TTC this month....I've often wondered about low progesterone and I wish my Dr. would just perscribe it as soon as I'm pregnant!!

Did the spotting scare you?  Was it a lot?  Have they checked your progesterone level?  What was it?


GOod luck, sweetie!!!

by stephd, Nov 06, 2006 12:00AM
I was on them too and took them the same time you are.  I never had any side effects from them (other than maybe being tired alot more)....BUT this could have been from being preggo and running after a 2 year old. That is why I was glad to take it at nite!!  Well good luck to you and I would say the sore bbs are from being preggo!!

Baby Dust!!

by wonderme, Nov 06, 2006 12:00AM
Hi.  I just posted this in another comment/question below.

Since you all are taking or considering taking progesterone suppositories, thought I would let you know what my doctor told me about the need to do it BEFORE getting pregnant.  

This is just what my doctor told me...be sure to check what you doctor has to say about this.

Hi. Haven't done progesterone supplementation but my doctor told me if it is needed it is best to do it BEFORE you get pregnant. Apparently once the pregnancy is established (corpus luteum which produces the progesterone) the progesterone supplements don't affect it. It is needed to help create a good, healthy CL cyst but after it doesn't really impact.

I also asked my doctor about needing progesterone after MC (how do you know if it MC b/c of lack of prog. or if prog. dropped b/c the pregnancy wasn't continuing) and was told that if you have fairly normal, regular cycles than you are most likely not progesterone deficient. Progesterone deficiency causes shorter luteal phases...if cycles are "normal/regular" than it is more likely that the MC was caused by a chromosomal abnormality.

How or why do you think you are deficient in progesterone?

Anyone else with insight?

Hope you're doing well. Take care.

by babytee, Nov 06, 2006 12:00AM
With the first pregnancy that m/c, I spotted almost the entire time (heavy enough for me to think that I was having my cycle) and I didn't even think I was pregnant until my bbs got sore and then I tested and it was positive. My numbers did not double as they were supposed to and I went on to m/c (never had prog checked). That time I wasn't really scared but I was just to the point where I wanted my body to be normal again. This time when I notice the spotting I told the dr immediately and she got very frustrated and told me to take progesterone supp (maybe she thought the first could have been prevented...I don't know) and I haven't seen a spot since (Thank God!). I had my 2nd beta done today and I'm waiting on my numbers now so I'll see how that goes. Best wishes and God bless you all!!

by stephd, Nov 06, 2006 12:00AM
To: wonderme
I dont know why a dr. would prescribe it to you after you are preggo if it doesnt work.  That just doesnt make sense to me.  My dr. prescribed it to me right after I found out I was preggo.  Just as a precaution...she didnt say I HAD to have it.  She said it helps build your lining more so the baby has a good place to implant and stay there.  Either I didnt need it or it helped cause I am 22 weeks now.  I think all doctors have their own opinion on things.  Just thought I would share my thoughts too!!

Baby Dust!

by Baby Angel Wings, Sep 26, 2007 11:34PM
My husband and I did IUI 5 days ago and the doctor put me on progesterone suppositories two days after the IUI.  Since taking the progesterone, my breast have become ENTIRELY sore.  And my nipples are painful to the touch!  But I've also noticed that I'm always sleepy and if I sit still, I feel very subtle "period like" cramps that come and go.  Does anybody else experience this?  I'm fearful that my period may be coming.

by JonesMama, Oct 02, 2007 10:23PM
To: Baby Angel Wings
I too am on prog supp and have the sore bb and slight cramps...I checked with my doc since this is my 3rd attempt and std that is normal, but I only feel like this when I insert them. and its just your uterus expanding, but I would check with the doc just to me for sure!

by lilybeth843, Oct 16, 2007 08:36PM

by paradise_beautiful, Aug 20, 2008 02:15AM
To: all of u
hi i m on progesterone too i was taking the progeterone its been a month now and i m now 12 weeks pregnant my dr checked on my blood test she said still low and was wondering after taking so many shots why its still low that thing made me worried and the fear of losing my child m jus so depress rite now and do not kno wat to do i m trying my best to fell better but u kno as i always stay alone at home with my kid and my husband comes late from his work so i have no one to talk and these things making me thin n think n think abt my pregnancy now dr put me on soppositories lets see wat happens now but those shots were making sleepy alot all day n nite i feel like unconscious if i dont sleep and headache its jus m goin through alot i hope i deliver a healthy and alive baby and i pray for u too the same and my best wishes who r ttc and the womans r pregnant please pray for me too.
paradise.

by Kari25, Aug 22, 2008 10:52PM
To: Paradise
Stay positive. i know it is hard. i am in your same situation. keep praying for a positive pregnancy and healthy baby. you are in my prayers. God won't give you anything you can't handle!

by mironach, Nov 19, 2008 02:08AM
To: wonderme
My wife had one miscarriage and after that her ob tested for low progesterone right after she got pregnant again.  The progesterone level was night increasing so we he put her on the supplement.  That pregnancy did good.  The next pregnancy was same situation.  Got pregnant, checked progesterone level, then checked again and it wasn't increasing so we did supplements again.  

by Katnelson, Nov 28, 2008 05:12PM
Hell there, I too am taking progesterone suppositories. I have had cramping and sore bbs.  I had in-vitro with icsi on witha transfer of 3 embryos on Nov.20.  since then I'm trying to saty calm but I just can not do it.  I am waiting to do a Blood test on Mon.Dec 1 to see if I'm pregnant or not.  But I still feel like I am getting my Period.  I have to say it is nice to see other woman having the same/similar effects as myself.
Thank-you Ladies.

by Meech7, Nov 29, 2008 11:37AM
To: Katnelson
Hi,  I had IUI and was taking Menopur injections and now on prometrium (progesterone) suppositories. I also feel little twinges, sore bbs and bloating. I guess these are side effects from the progesterone??? I was hoping they were pregnancy symtoms...but maybe not. I test on Wednesday, Dec. 3.

by kellykid, Dec 01, 2008 02:11AM
To: Katnelson
My doctor put me on 100mg at bedtime also, my side effects started right away. Before the progesterone I felt sick and threw up once in a while. Once I started them though, it was almost instantly I started throwing up every hour or whenever I ate or drank anything. I also felt tired all the time and generally just felt ****** and cranky. I forgot to take them and all those symptoms practically went away, as soon as I took them again they were back. So like I said my side effects were right away and pretty bad, but I think it was because my progesterone wasn't very low to begin with, 14.7 I'm told they like it to be at least 15.

by Meech7, Dec 01, 2008 05:38PM
Do any of you know if progesterone can make your period start earlier? I'm having very mild spotting (light pink to brownish) and my period is schedule to arrive on Sunday. I'm always consistent. Any advice would be greatly appreciated!

by jenbelli, Dec 06, 2008 10:28PM
I began the suppositories Weds. - the day after my "3 day timed intercourse" days =)  I didn't know you had to lie down after -- so I feel a lot of wetting, will try laying down next time =)  I find out if preg on the 15th, so let's hope it worked.  My infertility doctor prescribed the progesterone due to 2 past miscarriages -- apparently I just can't hold the pregnancies.  Thanks for all the comments -- so helpful!

by Jen1001, Dec 12, 2008 09:49AM
Hi,  I'm a little over 5 weeks pregnant and had my HCG tested this AM and am anxiously waiting for the results.  I have cramping and some reddish spotting today so I'm quite worried.  I have been on 200 2x/day progesterone suppositories since 3 days after ovulation.  I'm wondering if this could be a chemical pregnancy that the progesterone is delaying happening?  Hopefully not, but I've had 3 miscarriages in the last year so it's tough to be positive.... Has anyone had a chemical pregnancy while on progesterone supplements?   Jen

by allycat83, Feb 07, 2009 12:28PM
I am 8 wks pregnant and on 100 2Xday suppositories for about two weeks. I recently stopped taking them for 2 days b/c I was out. About 48 hours after being off, I started spotting a bright red. I am now back on, but have only taken it once. Does any one know if this is common?? When I took the first one today, I had some cramp like feelings. I am so worried right now. Does anyone have any advice or experience with this?? Good luck to all of you and God Bless!!

by amandaR26, Mar 11, 2009 12:31PM
To: all
I am on progesterone also. i am having period like symtoms-cramping, horrible back pain, stomach pain that comes and goes, and a temp of 99.5. i am going in for a pregnancy blood test sunday. do you think its too early to take a hpt? i have in vitro transfer a week ago today?

by samanthaone, Mar 12, 2009 01:33PM
To: all
i found out i was pregnant at 3 weeks my doctor put me on progesterone  suppositories  once in the morning and once before bed time to help me keep my baby now i'm 7 weeks and counting but i also go in every week for a check up to see if everything is ok i had 3 m/c's and one ectopic pregnancy and i haven't really had any side effects... . so good luck to you all

by ali1002, Mar 16, 2009 10:04PM
To: babytee
I just found out I was pregnant about a week and a half ago.  I immediatly went to the doctor because I have had 4 miscarraiges in the past.  I was told that I was about 4-5 weeks.  She took my blood on a Wednesday, and then again on a Friday.  She called me today to tell me that my progesterone is very low and wants me on a progesterone suppository.  I am willing to do anything to make sure this is a healthy pregnancy.  What I am worried about is that some information that I have found says that if you aren't on progesterone before you get pregnant that it doesnt help, and then some information that I find says that it does help.  I'm just confused as to what the information actually is.  Anything that anyone knows would be greatly appreciated!!  Thanks!!
Ali
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