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As long as the shot is in the muscle (not the blood vessel), progesterone injections are effectiveEffective strength cough syrup. The only reason they have you inject it in the hipHip joint replacement Hip pain is because it hurts less there. It could theoretically be injected into the thigh, it just hurts. If you are drawing out the needle slightly after the initial poke to be sure you haven't hit a blood vessel, you are fine.