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Maternal  (Expert Forum)
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HCG doubling, time of day,etc.
Patient medical question and answer from The Maternal and Child Health Forum. Health topic area and articles about newborn care

HCG doubling, time of day,etc.

by Loraine__0, Jan 15, 1999 12:00AM

  Hi--I know that you answer lot of questions about HCG but I hope that you can
  answer mine, too.  I am approximately 4 1/2 weeks pregnant (since LMP).  On Monday
  (1/11) my HCG was 331.  I had it done again at a different lab on Thursday (1/14)--
  three days later at a different lab and it was 656.  Is there variation between
  labs that could explain a less than doubling over 3 days.  Are my HCG values
  close enough to doubling that they are likely to be OK?  Does the time of day
  that the blood was drawn have an effect?
Dear Lorraine:
The time of day does not make a difference: hCG is not secreted in a daily cycle pattern. Compairison of values between different laboratories is difficult because of what is called inter-assay variation and because labs may use different standards giving a different absolute measure. The range of rise over 2-3 days is between 66% as the low at 2 days and 233% as the high at 3 days.
Serial values measured in the same laboratory would be the most helpful information.
This information is provided for education purposes and is not a medical consultation. If you have specific questionsxplease contact your physician.
Keywords: hCG




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