Recurrent fevers & Neutropenia

Posted By Ann  Alex on February 14, 1999 at 20:31:20:







Previously healthy white male 1 year 11 months old. History of 8 months of recurrent fever and intermittent neutropenia.  Fevers come every 18 - 28 days.  Testing for cyclic neutropenia initially showed neutropenia at anticipated time, fever as excepted then no further cycling during the following 6 weeks of study.  Fevers are 103-105 and last 2-5 days usually with no other symptoms (occasionally diarrhea & rash, stomatitis & gingivitis)  No history of otitis media or strep - when evaluated no cause of infection found.  Immune studies normal, EBV studies negative, HIV negative, chest x-ray negative, phyiscal exam normal except presence of small pea sized nodules in lymph nodes under the chin. Mother has a history of MS - no other family history of note.   Where do we go from here ?