The main thing for you to understand is that estrogen and thyroid hormones are linked together. When your estrogen is higher, your thyroid medication needs increase. So you need to work with your endocrinologist to make sure you are receiving the correct dose of thyroid as you stay on the patch or other estrogens.
As you know Lexapro is for depression and anxiety. If you had these symptoms before you went into perimenopause, then it might be a reasonable treatment. But if the symptoms came since the perimenopause window you are in, there is a good chance they will be effectively treated by getting the dosages of thyroid and estrogen hormones balanced. If you are now mostly needing treatment for anxiety and depression, it could also be very helpful to see a mental health specialist who can talk with you about why you are feeling that way. Sometimes that can eliminate the need for medication all together.
Machelle Seibel, MD
Cydnee