Hysterectomy and estrogen

I had a complete hysterectomy 10 years ago for endometriosis and I have been on estrogen since that time.  At first I was on a combination estrogen/testosterone but after I had major hair loss I started with just pure estrogen.  I take Estradial .5mg.  My concern is the length of time I have been on this drug and it's effects on my body.  I tried to stop 2 yrs ago, but had major problems with hot flashes, depression, lack of sleep & weight gain.  So the dr. put me back on at this low dose.  I also take meds for high blood pressure, high cholestrol & synthroid.  I just recently stared acid reflux & IBS meds also.  I am falling apart at the age of 44 and I feel it started with the hysterectomy.  I read so many different things about estrogen and I really just need some advice.  Since I have been on pure estrogen for this length of time without cancer issues & heart problems should this be a problem to continue for the rest of my life or should I look at getting off estrogen.  I have pap tests & mamograms yearly and also see the doctor once a year for blood tests.  Any advice would help and I appreciate your time ~ Thanks ~

[Machelle Seibel, MD]

A. Taking estrogen or not is a very big issue for women and there is not an absolute one answer. I will try to answer it for you the best I can. To take estrogen, one has to weigh the benefits against the risks. For you, the benefits are that it helps with hot flashes, sleep, depression and weight (which could be due to eating more if you