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Destroyed receptors stop disease?

Destroyed receptors stop disease?

I'm very interested whether you can simply destroy cell receptors with custom inhibitors (or other) and stop a variety of diseases (ex: HIV).  I've been told by some doctors that the receptor is unnecessary and could be disabled so why can't/hasn't this been done to stop many diseases?
Please email me directly if you have time to answer (***@****) and thanks a lot for any help and your time
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