Paresthesia is an unusual but possible side effect of the
SerotoninSerum serotonin level Specific Reuptake Inhibitors (SSRIs), including Zoloft, Paxil, Prozac, Celexa, and Luvox. It is difficult to predict if the paresthesia will resolve or not. If medical or dermatological causes of the paresthesia have been excluded, your treating physician/psychiatrist may consider treating you with an anti-histaminic medication such as Benadryl, or switch you to a non-SSRI antidepressant such as Wellbutrin or Remeron.
Dysthesias are common on zoloft in the startup period. Benzos will usually help with this as will beta blockers.
The beta blockers blunt the effect, but usually do not stop it.
Klonopin is usually used for this type of side effect & is probably the best choice. It tends to abort the adrenergic surges that the dysthesia is accompanied by.