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Mental Health (Expert Forum)
Clozapine effectiveness in the presence of other meds
Questions posted in the Mental Health forum are being answered by Dr. Roger L. Gould, author of the Mastering Stress and Depression program and affiliated with the UCLA. Department of Psychiatry. Topics covered include anger, attention deficit disorder (ADD) , bipolar disorder , dementia , electroconvulsive therapy (ECT) , learning disabilities, memory, obsessive compulsive disorder (OCD) , panic , personality disorders, phobias , post-traumatic stress disorder (PTSD) , schizophrenia , stress , transitions, and work problems.
Doctor's Answer
by HFHS MD - RG, Jun 06, 2000 12:00AM
The information packet of Clozaril indicates that the risks of using Clozaril in combination with other drugs have not been systematically evaluated.
However, the concomitant use of Clozaril with other drugs (like Trilafon)metabolized by a liver enzyme named cytochrome 450 2D6 should be approached with caution because these individuals may develop higher concentrations of Clozaril in the blood that may cause an increase incidence of side effects from the Clozaril.
However, the concomitant use of Clozaril with other drugs (like Trilafon)metabolized by a liver enzyme named cytochrome 450 2D6 should be approached with caution because these individuals may develop higher concentrations of Clozaril in the blood that may cause an increase incidence of side effects from the Clozaril.
