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Mental Health (Expert Forum)

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Combining Zoloft with a TCA

Answered by

Roger Gould, M.D. - Mental Health, Wellness

Questions posted in the Mental Health forum are being answered by Dr. Roger L. Gould, author of the Mastering Stress and Depression program and affiliated with the UCLA. Department of Psychiatry. Topics covered include anger, attention deficit disorder (ADD) , bipolar disorder , dementia , electroconvulsive therapy (ECT) , learning disabilities, memory, obsessive compulsive disorder (OCD) , panic , personality disorders, phobias , post-traumatic stress disorder (PTSD) , schizophrenia , stress , transitions, and work problems.

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MedHelp Member's Question

Combining Zoloft with a TCA

by Sandra1400, Mar 26, 2004 12:00AM

Tags: Zoloft, mental, Health, Mental Health, doxepin, Fibromyalgia, Pain, serotonin, tertiary, tricyclic

I began Zoloft, 25 mg., yesterday. I am also taking a tertiary tricyclic (Doxepin, 40 mg./day) for fibromyalgia. Is there any contraindication to combining these two meds? Thank you. Sandra1400

Doctor's Answer

by Roger Gould, M.D.

, Mar 27, 2004 12:00AM

These combinations have been used safely but you must be careful since the Doxepin has some of the same effects as Zoloft on serotonin, and the two may be addictive, and if you have pain and are sensitive, that makes a difference. Be sure and cover this with your doctor to be safe.

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