Dear Laura,
Imipramine (Tofranil) is a tricyclic antidepressant that is used in the treatment of depression and anxiety. Side effects such as low blood pressure, palpitations, heart problems, disorientation, delusions, insomnia, anxiety, nightmares, tingling, numbness, incoordination, dry mouth, blurred vision, jaundice etc. can result from Tofranil use. Zantac can cause some of these side effects. At present there are several newer medications that are available in the market , which were proven to be safe and effective in the treatment of anxiety.
I would recommend that you discuss with your physician/psychiatrist in detail about your concerns. A change in medication may help relieve your anxiety. I hope this information is helpful to you.