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Mental Health  (Expert Forum)
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Long Term Side Effects to Zoloft
Answered by
Roger Gould, M.D. - Mental Health, Wellness
Questions posted in the Mental Health forum are being answered by Dr. Roger L. Gould, author of the Mastering Stress and Depression program and affiliated with the UCLA. Department of Psychiatry. Topics covered include anger, attention deficit disorder (ADD) , bipolar disorder , dementia , electroconvulsive therapy (ECT) , learning disabilities, memory, obsessive compulsive disorder (OCD) , panic , personality disorders, phobias , post-traumatic stress disorder (PTSD) , schizophrenia , stress , transitions, and work problems.

Long Term Side Effects to Zoloft

by autumn, Aug 05, 2001 12:00AM
Dear Dr. Gould

I am a 38 yr. old female, who has suffered with depression off and on all of my life.  About 6 years ago, I was hospitalized with severe depression, panic and anxiety disorder.  In the past I have tried to get off the medication only to have all the symptoms reappear.  I have been told that my brain doesnot produce Serotonine and that I will probably be on the medication for the rest of my life.  I take 100mg a day.  I have recently developed cataracts, and I am scheduled for surgery in Sept.  My question is:  Are there any long term side effects from this drug? If there is what are they?

I thank-you for your time concerning this matter.

Sincerely
Autumn

by Roger Gould, M.D., Aug 13, 2001 12:00AM
At this time, there are no long term effects of Zoloft. These are still being studied, but too date it looks like a safe long term drug.
Member Comments (8)

by KRAIG, Aug 05, 2001 12:00AM
I to am on zoloft and have been wondering the same thing, as far as i can find the longest longterm studies were only for 8 weeks in patientes who wernt hospitalized.

by beanagator, Aug 07, 2001 12:00AM
I have been on Prozac for three years, then on Aropax (Paxil) for two years.  I would also be interested in knowing about long term side effects, because every time I come off my meds, I experience a profound episode of depression within three or four months, which makes me think I will be taking some kind of drug for a long time.  I have heard horror stories about tics and uncontrollable behaviours, some of which have been associated with SSRI medications.
beanagator

by kell26, Aug 07, 2001 12:00AM
I was on Luvox for a year, when I came off it, I had horrible headaches and I felt dizzy for a few weeks. It all subsided eventually. I too heard about tics and stuff, but I think it is pretty safe to say that is rare, you should be fine. I am not a doctor, but I do have faith in our medications of today. They are there to help.

by Toothygrin, Aug 08, 2001 12:00AM
I have been on Zoloft for about 4 years. When I forget to take my dose in the morning I experience severe vertigo and/or a headache.  Is this normal?

Thanks

by beanagator, Aug 12, 2001 12:00AM
I have been taking Paxil for about two years.  If I forget my morning dose, I experience feelings of dizziness, things feeling like they are about to slip out of focus.  I also feel jumpy and not quite right.  It goes away when I take my next dose, but I had the same feeling when I was coming off it.  the trick was to taper off really gradually, which was hard to do.  I didn't have the same experience when I was on Prozac and would forget to take it.

by hannahsmith, Sep 07, 2001 12:00AM
I was on SSRI's for a few months and had severe side effects from them for which i was hospitalised. After the last dose, the side-effects took months to disappear. It has now been two years and i have still not recovered from the side effects of the drug (electric shock sensations, pressure behind my eyes, sickness, and vertigo, to name just a few). My doctors have just told me that it must have caused a sensitivity or a 'rewiring' in my brain and that it will take some time for my mind to rebalance itself. so, yes i do believe that SSRI's can cause long term effects.

by Darla52, Nov 08, 2001 12:00AM
I have several questions about Zoloft.  My daughter has been taking it for several years now. 50mg a day. Recently, she has been feeling severely fatigued to the point of not being able to get out of bed or functioning at work. She is feeling as though she is going insane she says. Do most Zolot users eventially need to up the dosage as time goes by?? When a doctor prescribes this medication, how do they know if the mind produces enough Serotonin... is there a test??  Thanks for any information everyone.......
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