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Mental Health  (Expert Forum)
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Long term medication side effects, blurred vision
Answered by
Roger Gould, M.D. - Mental Health, Wellness
Questions posted in the Mental Health forum are being answered by Dr. Roger L. Gould, author of the Mastering Stress and Depression program and affiliated with the UCLA. Department of Psychiatry. Topics covered include anger, attention deficit disorder (ADD) , bipolar disorder , dementia , electroconvulsive therapy (ECT) , learning disabilities, memory, obsessive compulsive disorder (OCD) , panic , personality disorders, phobias , post-traumatic stress disorder (PTSD) , schizophrenia , stress , transitions, and work problems.

Long term medication side effects, blurred vision

by gptgem, Jan 07, 2004 12:00AM
After experiencing sudden onset of bilateral loss of vision, I was seen in an ER, the MD ruled out retinal detachment, glaucoma other critical issues, he did observe some change inthe optic nerves.  He postulated side effects from long term (10yr) use of Zoloft 100mg, Trazadone 100mg, and Serax, (oxazepam 10mg) BID. He also recommended immediate discontinuance of all medication. My questions:

* have you ever heard of side effects of sudden onset severe loss of vision of any of the mentioned drugs, or combination as above.

* should we discontinue the medication, and should it be tapered off rather than immediately discontinued.

The medication has effectively managed what has been a life long battle with depression, which has run in our family.

by Roger Gould, M.D., Jan 07, 2004 12:00AM
I have not heard of this.  I would not discontinue until I talked to an opthamologist about that, and would think about talking to a neurologist as well to check out the episode of bilateral loss of vision.
Member Comments (5)

by Try_to_be_social, Jan 07, 2004 12:00AM
To: gptgem
It is a good idea for you to have a second opinion from another opthalmologist and probably psychopharmacologist. If your drugs caused bilateral sudden visual loss they should be withdrawn from the markets all over the world immediately. I hope this is not your idiosychcratic reaction to the drugs. It is very unlikely that your drugs cause such unknown problem after 10 years. And such problem should not be ascribed to a combination of 3 drugs because each of which has its own special untoward effects and there is no documented drug interaction causes sudden visual loss. Never should your drugs be discontinued abruptly after 10 years. Zoloft and Tradadone can be tapperd off in 3 weeks but Serax in 2 months. The former can be replaced by Effexor and serax by Klonopin. What actually are the changes in the optic nerves that you have to pursue?

by gptgem, Jan 08, 2004 12:00AM
The physician stated that the optic nerve was white indicating atrophy.

by Try_to_be_social, Jan 09, 2004 12:00AM
To: gptgem
Please refer to <a href=http://www.ehendrick.org/healthy/000988.htm>http://www.ehendrick.org/healthy/000988.htm</a>. It seems that there is no relationship between your psychotropic drugs and optic atrophy.

by deb723, Mar 24, 2004 12:00AM
I am currently doing research for an upcoming book which deals with the side effects and withdrawals people have experienced from Effexor XR and other (like) anti-depressants. I am interested in receiving any information current or former users would like to share concerning their experiences with these drugs. Please email me @:
beach-***@****
and thanks!
deb
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