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Mental Health (Expert Forum)
Re: paxil and side effects
Questions posted in the Mental Health forum are being answered by Dr. Roger L. Gould, author of the Mastering Stress and Depression program and affiliated with the UCLA. Department of Psychiatry. Topics covered include anger, attention deficit disorder (ADD) , bipolar disorder , dementia , electroconvulsive therapy (ECT) , learning disabilities, memory, obsessive compulsive disorder (OCD) , panic , personality disorders, phobias , post-traumatic stress disorder (PTSD) , schizophrenia , stress , transitions, and work problems.
Re: paxil and side effects
by HFHS M.D.-HG, Jan 01, 1995 12:00AM
Posted By HFHS M.D. -HG on April 16, 1999 at 14:22:39
Topic Area: Depression
about a month ago i started taking paxil for my manic depression,
i had to stop taking it because of uncontrollable bruising. my
doctor has sent me for blood tests, but i am still waiting for the
results. i have heard that paxil is hard on your liver, is this
causing the bruising or is it something else?
Dear Kris,
Paxil (Paroxetine) is one of the SSRI's (Serotonin specific Reuptake Inhibitors) which is used for depression, OCD (obsessive compulsive disorder) and Panic disorder. Paxil is metabolized in liver. Increased plasma concentrations of Paxil occur in people with kidney and liver diseases. There have been rare reports of abnormal bleeding associated with Paxil use. Eventhough a causal relationship to Paxil is unclear, impaired platelet aggregation (platelets help clot blood) may result from depletion of serotonin in the platelets which can contribute to abnormal bleeding. Bruising may be unrelated to paxil . A thorough medical evaluation is needed to rule out any physical causes for bleeding.
Discuss with your physician in detail about your concerns. I hope this information is helpful to you. This information is provided for educational purposes only and should not be replaced by evaluation with a physician.
Key words: Paxil
Follow Ups:
Topic Area: Depression
about a month ago i started taking paxil for my manic depression,
i had to stop taking it because of uncontrollable bruising. my
doctor has sent me for blood tests, but i am still waiting for the
results. i have heard that paxil is hard on your liver, is this
causing the bruising or is it something else?
Dear Kris,
Paxil (Paroxetine) is one of the SSRI's (Serotonin specific Reuptake Inhibitors) which is used for depression, OCD (obsessive compulsive disorder) and Panic disorder. Paxil is metabolized in liver. Increased plasma concentrations of Paxil occur in people with kidney and liver diseases. There have been rare reports of abnormal bleeding associated with Paxil use. Eventhough a causal relationship to Paxil is unclear, impaired platelet aggregation (platelets help clot blood) may result from depletion of serotonin in the platelets which can contribute to abnormal bleeding. Bruising may be unrelated to paxil . A thorough medical evaluation is needed to rule out any physical causes for bleeding.
Discuss with your physician in detail about your concerns. I hope this information is helpful to you. This information is provided for educational purposes only and should not be replaced by evaluation with a physician.
Key words: Paxil
Follow Ups:
