You may not have any withdrawal symptoms. It varies. But you should not go off cold turkey because there is still some possibility of seizures to consider. Space your last three pills and
scrape up enough money so you can taper down over a three week period, going down to minimal dose 3 days apart for last week, then stop, and continue with the klonopin.
Most drug companies have these types of programs to help people such as yourself.
Also -- have you checked to see if your college/university has a medical plan that includes RX coverage? This might be an option too.
This is my first time on any forum. I've been a reader but I've never logged in and shared. I'd been on Effexor to help control the pain from Fibromyalgia and Chronic Fatigue Syndrome (300mg a day) but gained a ton of weight. Also I had severe itching syndrome (my own term) and would need to sleep with a hair brush (new of course) just to get through the night. Naturally that causes depression even if you're on antidepressents. And the weight gain seemed to only hurt my chronic pain condition.
But I was also just tested for ADD about two months ago - have it by the way, and now the testing center wants me to go on Wellbutrin for both depression and ADD. In preparation I went off the Effexor even slower than they recommended. Even then the symptoms made me feel like I was going to fall off the face of the earth. I couldn't turn my head without getting dizzy, but more than that I just felt like I was helpless to funtion on my own.
Now completely off Effexor I feel a bit better, but I just had a total hysterectomy 2 weeks ago and the pain and complications due to an infection has caused a Fibromyalgia flare up and you got it - more depression.
I'm really looking forward to beginning the Wellbutrin for the depression but I'm wondering if anyone has had success with combination therapy from an ADD stimulant drug in addtion to Wellbutrin. The testing center said it's possible to do both but before I go to my doctor and discuss options I'd just like to know a bit more from people who've been there.
Thanks and God Bless
today is Day ONE for me
- trying to self-wean off of this horrid drug.
I have been on 150mg a day of XR for almost one year.
Yes, it did help me extremely thru some really, really rough times but now I believe the negative side effects outweigh the positive. (Also, no more insurance...)
I have not been able to sleep, the weight gain is disgusting,
but one of the worst side effects (and this is very hard to admit) is that this crazy drug makes me actually "crave" alcohol.
That was even hard to type :(
Am I the only one?
I want to get away from the E XR Monster.
So; I have chosen to try 75mg a day for 2 weeks and then 37.5mg a day for two weeks - Any advice on this logic? Any success stories out there?
Also interested in which vitamins might help.
Thanks to all & God bless
I will say a special prayer for all of you that are experiencing these same effects.
Take Care!!
Thank you!!
THANKING YOU GRATEFULLY
P.G.
Although not exactly sure why, I feel that I no longer require the medication. It likely has something to do with a decrease in my overall stress level which was associated with my professional training.
Recently, I decided it was time to stop the medication. I was on a fairly large dose, and basically did a gradual taper over a 3-week period. I had no withdrawal symptoms until completely stopping the medication 2 days ago. Prior to stopping completely, the last step in the taper was around 35 mg per day. Today is day #3 off the medication and I am definitely feeling it. At this point, the symptoms are very much like those I experienced coming off the Paxil, so I definitely think this is something common to SSRI-type drugs. This is what I have noticed; 1) A general sense of cognitive haziness making it more difficult to focus/concentrate, 2) A feeling of dizziness with anything more than very gradual turning of the head which many describe as "brain bounce." I also can reproduce this feeling at time by simply blinking my eyes or shifting my focus point, 3) A heightened sense of anxiety which I think is totally understandable given the unpleasant nature of the above, 4) Some nausea, especially "car sickness" when riding, not driving, especially if I try to read something, 5) Some diarrhea, which is what you would expect after stopping a medication which has "anticholinergic" properties (You probably noticed that Effexor can cause relative constipation. This is a typical anticholinergic side effect. Another is dry mouth/decreased salivation. It occurs to me as write this that I am salivating more. Again, this "rebound effect" is what one would expect after stopping such a medication.) I am not having a recurrence of my typical depressive symptoms, and strangely my mood is often upbeat.
Flat out, this withdrawal phenomenon is real and it really stinks!!! However, I am dealing with it much better (at this point) than I did coming off the Paxil because I have a sense of what to expect. When I stopped the Paxil, I had no idea what was happening and it was SCARY. I want to emphasize that simply knowing what to expect has, thus far, made a huge difference. I know that what I am feeling is withdrawal from a drug, nothing more. I am not "going crazy." Although it is more challenging, I can still function well at work and at home. I know that this will improve (it did with the Paxil after about 3 weeks), and in the end I am confident that I will be better for it. I hope this helps you guys, I know it has helped me just writing it.
KWW
Although not exactly sure why, I feel that I no longer require the medication. It likely has something to do with a decrease in my overall stress level which was associated with my professional training.
Recently, I decided it was time to stop the medication. I was on a fairly large dose, and basically did a gradual taper over a 3-week period. I had no withdrawal symptoms until completely stopping the medication 2 days ago. Prior to stopping completely, the last step in the taper was around 35 mg per day. Today is day #3 off the medication and I am definitely feeling it. At this point, the symptoms are very much like those I experienced coming off the Paxil, so I definitely think this is something common to SSRI-type drugs. This is what I have noticed; 1) A general sense of cognitive haziness making it more difficult to focus/concentrate, 2) A feeling of dizziness with anything more than very gradual turning of the head which many describe as "brain bounce." I also can reproduce this feeling at time by simply blinking my eyes or shifting my focus point, 3) A heightened sense of anxiety which I think is totally understandable given the unpleasant nature of the above, 4) Some nausea, especially "car sickness" when riding, not driving, especially if I try to read something, 5) Some diarrhea, which is what you would expect after stopping a medication which has "anticholinergic" properties (You probably noticed that Effexor can cause relative constipation. This is a typical anticholinergic side effect. Another is dry mouth/decreased salivation. It occurs to me as write this that I am salivating more. Again, this "rebound effect" is what one would expect after stopping such a medication.) I am not having a recurrence of my typical depressive symptoms, and strangely my mood is often upbeat.
Flat out, this withdrawal phenomenon is real and it really stinks!!! However, I am dealing with it much better (at this point) than I did coming off the Paxil because I have a sense of what to expect. When I stopped the Paxil, I had no idea what was happening and it was SCARY. I want to emphasize that simply knowing what to expect has, thus far, made a huge difference. I know that what I am feeling is withdrawal from a drug, nothing more. I am not "going crazy." Although it is more challenging, I can still function well at work and at home. I know that this will improve (it did with the Paxil after about 3 weeks), and in the end I am confident that I will be better for it. I hope this helps you guys, I know it has helped me just writing it.
KWW
My question is, given the extremely short life of this drug in the system, what is the most effective strategy for withdrawal. This drug is not like Zoloft where each day lowers the amount of the drug in your system by half [If you just stopped taking the drug cold turkey, which I don’t recommend, Day 1-100 mg, Day 2-50 mg, Day 3-25 mg, Day 4-12.5 mg and so on]. My understanding is with Effexor XR that active part of the drug is completely out of your system in less than 24 hours, when you take your dose each day you are actually starting fresh. If this is true then the tapering discussed in this and other threads about Effexor doesn’t seem right. Seems to me by reducing the dose from one day to the next you are in fact going through a whole cycle of re-introduction and withdrawal each and every day, actually many mini-withdrawals. Does anyone have thoughts about a withdrawal regimen that reduces the doses but over a shorter time cycle 75 mg in the morning, 37.5 mg 15 hours later, half that 15 hours later and so on until you reach a dose so small that your body no longer reacts. Overall I’d say this is a not a good drug and would not recommend it to anyone, even at the lowest doses. It should probably not be on the market. I intend to replace it with another SSRI, something with less dramatic side effects as soon as I can figure out a way to get off of it
Hi, Thanks for the informative posts. I was on effexor only for a week and half in which time I have taken 7 37.5 and 5 of 75 tablets. Can I stop cold turkey... If I do what are the sideeffects and how long will it take for me to get rid of all the side effects. Please help....
My dr, a nuerologist who specializes in new onset of chronic headaches, just prescribed Effexor XR for my daily, chronic headaches that I have had since I gave birth to my daughter in June 05. He said take 37.5mg first week, 75mg second week, and 150 mg third and fourth week. I have taken the 37.5 for three days now and feel very nauseated. I am also breastfeeding and trying to wean, which concerns me but I have been told by several reliable sources that it is relatively safe.
I am so scared now after reading all the withdrawl problems that people have had. I wonder if there are any alternatives out there for us.
Kathy
There have been a couple of times in the past that I forgot to take my medication and the withdrawals were TERRIBLE. I went from 75 mg to a week of 37.5 mg a day and now 37.5 mg every other day. I have done the every other day for a week now and I am on my second day of not taking it and I must say that I am not doing very well.
Besides being terribly scared that I will never be able to stop taking this medication. I am having headaches, I want to puke, I can't sleep at night, I just want to bust out into tears, I can't think and feel as if I am in a fog. I also have these weird sensations in my head like a just took a whole handful of white cross tops.
Does anyone have any suggestions on how to deal with these unrully withdrawl symptoms?
Any suggestions to help this? Drink a ton of water? Wait it out...how long do these freakin brain zaps last? I am so frustrated.
I've been taking Effexor for over five years. I've been up to 150mg/day of Effexor XR and have now been down to 37.5mg/day for two days. I plan on staying at 37.5 for a week and then trying that amount every other day for a week.
I hope this time I can get off it for good. Previously I weaned myself off, did "okay" for a week and then 'crashed'. Just felt hopelessly depressed, and went back on the Effexor out of desperation.
The brain zaps are the worst, plus I'm already experiencing dizziness. I will try the ginger as suggested above, and perhaps also try the motion sickness tablet (if necessary).
In my opinion, Effexor is a hellish drug --- and if I had known how almost impossibly difficult it is to quit this drug, I never would have started it.
Good Luck to all of us.
How did it come to this?
who is responsible for our problems?
IS it our physicians who prescribed the drug and in my case never mentioned any of the side effects I have experienced..
OR is it us..a patient ..in a situation where we just really wanted to believe our dr and see the light at the end of the tunnel without looking / researching the medication further.
OR is it the drug company who obviously did not do enough testing or give enough information on how harmful this drug can be...
I have been on effexor for almost 3 years..now supplemented with wellbutrin and yes it has helped me get out of the darkness..but i have to say..I did most of the work..
I just cant believe how unfortunate it is that all of us and many more are going thru this horrible time and are not given the correct information or assistance.
I am not yet an ex effexor BUT i am in the process of weaning ..and it SUCKS!!
I am so glad I am not alone..but I would not wish this on my worst enemy..
the "electrical shocks:
nausea, Hunger ,shakes dizziness sweats, confusion sleepiness headaches itchy skin, weight gain (even if you are watching what you eat /active lifestyle) etc etc..
I dont know whether the pros outweigh the cons..
how come the drug company hasnt helped us?
is anyone aware of any contacts for help for me..?
sigh...
anyways..KEep going on..Life is a beautiful struggle..
focus on the little triumphs and go one day at a time..
Bless
especially the side effects..
Effexor XR helped me..but its hard to get off of it
Depression is a life long battle and when you are in the midst of it .. there seems like no way out..
Effexor helped me get to the point i could start helping myself..
It did help me too, to get back to having the will to live again, ...but at a very high price [seemingly unable to get OFF it!].
I suppose if one is in the depths of depression and ready to END it all (as I was!), then Effexor XR would be one of the answers.
It did work for me, where some of the other A.D.'s didn't.
However, five ...almost six years later, I'm still trying to get OFF the drug.
I'm on DAY SEVEN now at 37.5 mg/Effexor XR (trying to wean myself off it), and tonight I'm feeling very depressed again.
I'm going to try and ride it out...
Good Luck Everyone!
P.S. I do think that the makers of Effexor XR (and the physicians)should make people aware that this is a difficult, if not impossible drug, to come off of.
I would recommend this drug ..if you have tried other alternatives and nothing seems to be working because..no matter how hard this drug is to come off ..
I will take the side effects over the depression..
I just cant believe that my physician didnt make me aware of these side effects ..in fact..she told me that that side effects are RARE...and on all the information I have researched..I have not a read one single post on someone who takes who has taken effexor that did not have side effects...
all in all..with drugs or without...depression will not go away solely because of of taking a drug...
it helps
but i found it in my situation..it ultimately was all up to me..you need to change your life..and start by finding the happiness in the small things in life..and start working your way up...
have good positive people surronding you..and push yourself a little extra every day..
I dont know everyone stories on how they realized that they were more than just sad..more than in a bad mood..but take my word ..there is a light at the end of the tunnel...you will find it..but you need to try and work hard at it..every day...
Keep your heads up!
God Bless
I.) THE VARYING SYMPTONS OF WITHDRAWAL
II.) HOW TO TAPER OFF OF EFFEXOR
*****************************************************************
I.) THE VARYING SYMPTONS OF WITHDRAWAL:
PSYCHIATRIC SYMPTOMS:
That Mimic Depression
Crying spells, Worsened mood, Low energy (fatigue, lethargy, malaise); Trouble concentrating, Insomnia or trouble sleeping, Change in appetite, Suicidal thoughts, Suicide attempts
That Mimic Anxiety Disorders
Anxious, nervous, tense; Panic attacks (racing heart, breathless); Chest pain; Trembling, jittery, or shaking
Irritability and Aggression
Irritability, Agitation (restlessness, hyperactivity); Impulsivity, Aggressiveness, Self-harm, Homicidal thoughts or urges
Confusion and Memory Problems
Confusion or cognitive difficulties; Memory problems or forgetfulness
Mood Swings
Elevated mood (feeling high), Mood swings, Manic-like reactions
Hallucinations
Auditory hallucinations, Visual hallucinations
Dissociation
Feeling detached or unreal
Other
Excessive or intense dreaming, Nightmares
MEDICAL SYMPTOMS:
That Mimic the Flu
Flu-like aches and pains, Fever, Sweats, Chills, Runny nose, Sore eyes
That Mimic Gastroenteritis
Nausea, Vomiting, Diarrhea, Abdominal pain or cramps, Stomach bloating
Dizziness
Disequilibrium; Spinning, swaying, lightheaded; Hung over or waterlogged feeling, Unsteady gait, poor coordination, Motion sickness
Headache
Tremor
Sensory Abnormalities
Numbness, burning, or tingling; Electric zap-like sensations in the brain; Electric shock-like sensations in the body, Abnormal visual sensations, Ringing or other noises in the ears, Abnormal smells or tastes
Other
Drooling or excessive saliva, Slurred speech, Blurred vision; Muscle cramps, stiffness, twitches; Feeling of restless legs, Uncontrollable twitching of mouth.
VVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVV
II.) HOW TO TAPER OFF OF EFFEXOR
I have taken Effexor and my highest dose was 150mg XR/once a day (extended release capsules) for 1 1/2 years; I have been tapering for 8 months and I'm now at 28.06mg/for the day (using tablets). I have had minimal withdrawal to this point and I attribute that to the *very slow* tapering and cutting doseage's at a rate between 5-10% (and no more than that) each time.
Now for the how to's:
Instead of counting out granules (which really isn't accurate as granule capsule contents vary anywhere from 105 - 124 granules per capsule), use Effexor immediate release tablets. The only difference is that you will take one half of your tablet dose in the morning and twelve hours later take the second half of your dose.
Effexor tablets come in: 100mg, 75mg, 50mg, 37.50mg, and 25mg. You can purchase a "pill splitter" from any pharmacy--the cost about $4.00 (american money) and split your pills in half, quarters, and even eigths--(with a little practice for the 1/8s). Splitting tablets will enable you to have more control stepping done your medication. When I got to a dose that is in between one of the tablet sizes listed above, I respectfully requested from my doctor a prescription of two different amounts of tablets. If you are at 150mg Effexor XR, then ask for a prescription of 50mg tablets and 37.50mg tablets. Purchase a pill splitter at any pharmacy ($4.00).
Start out by taking the exact amount you are on now so that your body can adjust to your new dosing schedule. Here's how:
--Take one 50mg in the morning + 25mg (split one 50mg in half) = 75mg
--12 hours later take one 50mg + 25mg = 75mg
--75mg + 75mg = 150mg for the day
**Do this for two weeks and then start your tapering.**
Always take 5-10% of your last doseage amount, subtract that amount from your last doseage amount = your new doseage amount.
TO BEGIN TAPERING:
--150mg x 10% = 15mg
--150 - 15mg = 137.50mg
Take one 50mg + 18.75mg (cut one 37.50mg in half) = 68.75mg
--12 hours later take one 50mg + 18.75mg = 68.75mg
--68.75mg + 68.75mg = 137.50mg for the day
STAY AT THIS AMOUNT FOR ONE (1) MONTH - your brain chemistry needs to adjust.
**The next time you make a cut you will take 5-10% of 137.50mg**
**Always stay at your new doseage until you stablize--one month at the very least.**
*WHEN CUTTING YOUR PILLS* of differing milligrams, have some empty, clean, prescription bottles that are labeled (for example 18.75mg, 12.50mg, 9.37mg, 6.25mg, 4.66mg, etc.) so that you don't get them mixed up. As you cut smaller amounts it gets harder to distinguish what is what--the labeled bottles will keep you straight. Just be sure to put the correct amounts in the correct bottles!
*DON'T BE SUPRISED* as you get lower and lower on your dose that you may need more than 3-4 weeks to stablize; remember your brain is going through a HUGE change--give it the chance to even out. It's not important how long it takes to taper from dose to dose, it matters that you take your time!
*ALWAYS* take Effexor with food in your stomach and drink plenty of water.
Do *NOT* eat or drink anything containing GRAPFRUIT, it can create a serious toxic reaction.
*NEVER, EVER* take St. John's Wort or 5-HTP--they have a serotonin in them. Mixing them with an anti-depressant or taking then after you've been off of an anti-depressant for only a year of less can lead to SEROTONIN SYNDROME - a toxic and deadly condition. Click on the following link to find out about it: http://www.antidepressantsfacts.com/serotonin-syndrome-ADF.htm
*NEVER, EVER* take Effexor or any anti-depressant every other day--withdrawal will start and you will never get back on an even keel. I know, I know your doctor told you to do this, but MOST doctors are truely ignorant of the hell they are about to put you through doing this. If you are currently on this program get back to taking your dose everyday and after you are stabilized you can start your tapering.
*PLEASE TAKE THE TIME* to visit these webpages; they have critical and very helpful information for tapering:
http://www.antidepressantsfacts.com/reaction.htm
http://www.antidepressantsfacts.com/taper.htm
The best to everyone,
Sweettooth
*CAUTION* This method can ONLY be done with tablets. XR (extended release) versions of medications CANNOT use this method; it will lead to overdose.
Here is a better WATER TAPERING method than the previous one I had posted (which I have removed).
Equipment needed:
a tall lab cylinder that holds 250 ml
a small lab cylinder that holds 10 ml
a dropper or syringe
a mortar and pestle
a small battery-operated mixer
a continuing supply of the med. you are using
Process:
Grind the tablet in the mortar and pestle.
Fill the tall lab cylinder to a predetermined amount of water. Use this same amount of water each time you make a reduction. The amount you start with will determine just how small the cut is. Another words the greater amount of water you use, the fewer medicine particles per ml will be suspended in it. The less water you use the greater the amount of medicine particles per ml will be suspended in it.
How to determine the amount of cut you'll be making:
Divide your dose by the milliliters of water you intend to use to find the amount of drug per 1 ml of water.
Examples:
37.50mg Effexor tablet divided by 200ml of water = 0.1875mg per 1 ml of water.
37.50mg Effexor tablet divided by 150ml of water = 0.25mg per 1 ml of water.
Pour a little of the water in the cylinder onto the powdered drug and grind it some more. Then rinse the mortar into the battery-operated mixer, using the water in the cylinder until all of the powder in the mortar and on the pestle has gone into the mixer, as well as the rest of the water in the cylinder. The mortar will become colored from the dye used in the pills, do not be concerned about that.
Hit the spin button on the battery-operated mixer. This puts the drug particles into suspension in the water. There is no need for the pills to dissolve or be water soluble; putting the particles into suspension is sufficient to insure random dispersal for long enough to adjust your dosage.
While the mixer is still ON, take the dropper and remove a small amount of the water. Use the small lab cylinder to measure this amount to 1 ml. Discard this amount and drink the water that remains in the mixer. Then add a little more water from a cup and hit spin again to get all the residue out of the mixer and drink that. The next dose, repeat the process but discard 2mls of water and drink the rest.
The advantage to this method is that as long as you have a sufficient supply of tablets, you can reduce at your own rate and make tiny reductions. The brain doesn't differentiate between very small reductions of dose over a few days, but the cumulative cuts do add up so if you feel withdrawal setting in, STOP and let your body adjust.
Now all you have do is find the equipment. A Power Mixer can be obtained from www.bodybuilding.com. It's called the Personal Power Mixer. Or just go to www.Google.com and type in the words "Power Mixer", I'm sure you'll find lots of places that sell them and then you can look for the best price. The same thing goes for graduated cylinders and mortars and pestles. Here is website so you can at least see what they look like, www.pharmex.com.
I am not in anyway affiliated or profit from the above companies.
Sweettooth
She offered me a reduction schedule that lasted 5 days!! After 2 days I rang her and told her I would be doing my own reduction over the next month. What followed was one of the worst months of my life. I had one week off work and I have never been so sick in my life, vomiting, diareaha, nausea, painful heaadaches that dont respond to medication, fatigue, ringing in my ears. I had to go and stay at my mums and was completed incapacitated at times. I stablised on a lower dose so I could return to work, and decided to reduce my dose slightly every Friday and try and cop the worst of it over the weekend. I managed this for 3 weeks and went to work every day with these painful headaches and awful nausea. Nothing I took for the headaches helped, but ginger did help for the nausea.
I took my last Effexor dose 6 days ago. It was a a very low dose of 10 of those little balls from the XR capsule - equivalent of about 3 gms of the drug. I felt ok for the first 3 days, the physical withdrawals more or less have gone, but the last 3 days I have been "out of control". My emotions are all over the place, I cant stop crying, I am having suicidal thoughts (not that I am planning to follow through on them), I feel desperate and have not been able to go to work this week.
Is this normal? Did anyone else feel like this in the first week coming off the drug? How long does it last? I know that my doctor would say it is the depression symptoms returning but I know that is not the case - I did NOT feel like this before starting on Effexor. My doctors are ill informed about the side effects of taking this drug and coming off it and I feel that they think I have exaggerated the effects I have experienced the last month. It makes me so mad.
Anyway, thanks for reading, and all replies very much appreciated.
I have been on 150 mg for one year. The few times I forgot to take it was absolute hell. Dizziness, empty head, very spooky the first time, until I realized it was because I had forgotten to take my pills.
I gain 20 pounds over one year from 125 to 145. Doctor told me it was a rare effect and she did not think it was related to effexor! Does anyone know if loosing that weight will be facilitated by stopping the medication? I am afraid not...
I tappered my self down to 37.5mg per two days without any difficuties. But have not been able to make it to evry three days. I have been at this dose for almost six weeks, but if I pass more than 12 hours after pill time, I start being so depressed, crazy, in a very bad humor and full of tears… it took me few times to admit it was related to trying to get off the pill. I thought my dose was so little and probalby just placebo like!... Again doctor said she was surprised such a low dose would have this effect. But it was for sure worth staying on it!! So I decided then to stay on that little dose.
But last night I forgot to take it, and all these very strong emotions were there again. So I drove like crazy home towards my pills. After only few hours every thing became again magically just fine again. And few hours ago I typed "stopping Effexor" and I am grateful I did..
So I will choose the right moment and try again to get off that 37,5 every two days. I will start taking half a capsule and counting the little white balls the same way someone else did it. Unfortunately, I will have to do this without my doctor and than have to find another one. If anyone has better advise please do.
There is bad stuff on the market, but these web sites are for sure a wonderful thing! Thanks for sharing and good luck to all of you trying to get off!
Effexor was very effective in pulling me out of a depression. In retrospect I feel that since the depression I experienced was clearly related to being overwhelmed by some stressful events, I think that I might have been better off getting help from a person instead of the drug. That's just a comment for anyone who might be considering Effexor.
I was very happy with the med after the first month, because it did exactly what it was supposed to do, the depression completely lifted. I can't say I was any happier, just less - depressed.
My personality changed significantly while on Effexor. I am normally a sweet and nurturing person who cares deeply about other people. Once I began to take Effexor, I found myself acting agressive from time to time, not hesitating - I had conflicts with co-workers and didn't hesitate to tell them just what I thought of them. I didn't mention this to my doctor. I'm not sure why. I think it was because I felt stronger and more empowered to express myself and I liked that, but at the same time, it's pretty important to weigh the benefits against the possible ramifications that real events can have on your relationships with others.
I gained a significant amount of weight, enough that it really shows: 30 pounds. New wardrobe anyone? Stretch knit is now my friend.
You wonder why the warning from Wyeth is not to consume alcohol with this drug. They don't explain it. For me, alcohol consumption went way up, no worries for me (the drug really does eliminate the anxiety that you might feel wondering if you're turning into an alcoholic, and I never had a hangover on Effexor!) My husband and I are a couple that used to enjoy a glass of wine with dinner, very moderate and mindful in our alcohol consumption and choices, we used to look forward to choosing and understanding wine, it has been one of our common interests - but that deteriorated quickly when I started taking Effexor. My husband was VERY concerned, especially when I started buying bottles of hard alcohol. He has luckily been supportive and stuck with me. I can imagine that under some circumstances this could be catastrophic. I think there's a real danger that this med can be very harmful if you enjoy wine, even just a little bit. (yes, that was pretty hard to type, wasn't it? It is a very loaded and very serious problem that people should consider.)
I am easing off for a couple of months and have reached the time to stop altogether. I was on 75mg daily for about 8 months and for the last month I took 37.5mg with no problems. Two weeks of skipping days with no problem. Four days ago I stopped altogether. Now I am getting the revving electrical brain thing when I am awake and although it's not painful, it's scary.
I noted that one person said that half the battle was knowing what to expect, and that's reassuring to me, since I think I can live with the withdrawl as long as it does not last too long. I really feel that being off Effexor is more important than the side effects coming off. Which leads me to my big question:
How long can I expect to have these revved up brain surges? It is enough to interrupt my normal activity. It's kind of like some kind of adrenaline but at the same time it's concentrating around my upper body. I would like some answers from people who have gotton completely off Effexor and now are completely side-effect free.
These are not happy pills. Effexor is a powerful medicine.
My advice to anyone trying to withdraw - if your doctor tells you to decrease over a matter of days, or to just stop taking Effexor altogether "Do not listen to them! They dont know what they are talking about!!" Listen to the people who have had to go through this before you. I have found doctors to be of no use at all through this experience.
Here is my advice for what it is worth:
1. Reduce very very slowly - I was only on the drug 3 weeks, yet it took me nearly 4 weeks to get off it! Go figure! If you are on a high dose and have been taking the drug for more than a few months, you will need to reduce over a period of a few months or even more.
2. Reduce your daily dose by about 10 - 15% if you can handle it, and stay there for 2 weeks before reducing again.
3. Dont listen to doctors who tell you to take the med every second or third day - when you do this you will just send your body into withdrawal. Because of the low half life of Effexor you will most probably start to feel sick if you miss a day.It is much better to take it every day and lower the dosage over time.
4. I have heard that the lower reductions just before you stop altogethr can be more horrible than the bigger ones - you may need to decrease more slowly as you get closer to coming off the drug completely. This means you will need to cut up pills, or break open the capsules.
The last week or so of my reduction went like this.
I opened the 75 mg XR release capsule and counted the granules - there were about 250, which meant roughly 3.3 granules was equal to 1 gram of the drug. On Friday I took 40 granules, Saturday 35 granules, Sunday 30 granules etc until the last day I took 10 granules.
The doctors will tell you not to do this but it is the only way I could get the doses small enough. Make sure you dont break or crush the granules - carefully pop them on your tongue and swallow or put them in a teaspoon of yoghurt or something.
Make sure you always eat and drink a big glass of water.
5. Other things that helped:
- Ginger for nausea - it doesnt take it away completely but does take the edge off
- Benedryl(diphenhydramine hydrocholoride). Depending on the country you are in it is sold as an antihistamine, or an OTC sleeping aid. These did seem to help me with the headaches and sleeping at night.
- I've seen other postings where people recommend taking fish oil supplements, which I did, but I dont know if it helped any. I'm sure its good for me anyways.
To all of you trying to deal with this horrible drug, be gentle with yourself - you may need to take time off work - personally I have had to take 8 days off work because of Effexor - I'm lucky I have an understanding boss.
Good luck everyone - you will get through this. Take care
Somethings I have heard that helps are,
dramamine, For dizziness and nausea
fish oil supplements
oils such as jasmine and lemongrass
omega 3
Some of these things I found just researching depression and natural treatments
It does help to know that I am not the only one who has expierenced this. I tell my family and they just dont understand what I am feeling.
My main mistake was letting my dr. give me just 7 pills. On the effexor website each time you step down you need to stay at that dose for at least 2 weeks before going down more.