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Mental Health  (Expert Forum)
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Which anti depressant does NOT cause weight gain?
Answered by
Roger Gould, M.D. - Mental Health, Wellness
Questions posted in the Mental Health forum are being answered by Dr. Roger L. Gould, author of the Mastering Stress and Depression program and affiliated with the UCLA. Department of Psychiatry. Topics covered include anger, attention deficit disorder (ADD) , bipolar disorder , dementia , electroconvulsive therapy (ECT) , learning disabilities, memory, obsessive compulsive disorder (OCD) , panic , personality disorders, phobias , post-traumatic stress disorder (PTSD) , schizophrenia , stress , transitions, and work problems.

Which anti depressant does NOT cause weight gain?

by Pavlova, Feb 04, 2005 12:00AM
Have been on Mirtazapine for nearly two years, and have so far put on 2stone! Am extremely upset at this, not to mention that my cholesterol has soared to 7.3.
My psychiatrist is not keen to change the drug but am gradually wearing her down by my constant whinging that I really do not want to go into my middle late years as a roly poly!!
Having spent hours on the internet looking for an antidepressant that will control my late onset depression (Started when I was 50-presumably menopausal) and not put on weight which as you can see by my cholesterol is not a good health profile. I do not smoke and my B/P is always low. No idea of family genes as am adopted.
I would be most grateful if you could suggest a medication that might be a good alternative to Mirtazapine. Wellbutrin or Cipramil spring to mind but need a medical head on this problem.
Thank you for taking the time to read this and hopefully offer some good advice.
One good thing is that The Psychiatrist does not see me on long term medication but wants it to continue for three yearsin total.
That still leaves me with another year to go!

by Roger Gould, M.D., Feb 04, 2005 12:00AM
Wellbutrin is the most frequently recommended medication when weight gain is an issue.  You can also get some help with the emotional eating patterns that cause weight gain by going to www.masteringfood.com
Member Comments (14)

by leigh47, Feb 05, 2005 12:00AM
I was on Wellbutrin for a few years and didn't gain a pound.
One month on Zoloft and I gained 5 pounds...and that was with working out 5 times per week at my gym. For some reason, some of the antidepressants make you feel hungry all the time and makes you crave the "dreaded" carbs.

I hope you feel better soon.

by Lerry, Feb 07, 2005 12:00AM
Hi,

I take Lovan 20 and sometimes I feel like skipping meals but have something to keep up my health.

by mcla, Feb 15, 2005 12:00AM
I have been taking Zoloft for a little over a month and have lost weight.  I do tend to lose weight when I am doing through stressful times.  The medication has been great for anxiety and depression.  I am not wanting to lose weight but I would rather lose than gain.  Zoloft may be a good alternative for you.

by Timmy256, Feb 15, 2005 12:00AM
Cymbalta is not supposed to cause weight gain.  I just stopped taking it and have had a hard time with dizzyness and brain zaps.  Anyone have this problem?

by AndyDep, Mar 18, 2005 12:00AM
I've been on mirtazepine for a year and have put on a stone and a half. (I don't eat much so it must be the meds)

A

(also on chlorpromazine and procycledene)

by iddm1981, Jun 22, 2005 12:00AM
I can't seem to find an anti-depressant that I can tolerate that doesn't make me gain weight.  I've tried Prozac, Lexapro, Wellbutrin, and now Cymbalta.  The wellbutrin gave me chest pain.  The others just don't do a whole lot for the depression, especially since I've added almost 30 lbs!!! (That's depressing in itself!)  It's not my diet.  I even tried eating 300 cal/day and still gained.  Now I'm just trying to eat sensibly.  A friend said her doctor put her on dexadrine with the anti-depressant.  Anyone out there with experience on that or have any other suggestions of meds to try?  I can't take the tricyclics due to other health problems.  Also, my cholesterol went sky high once I did start on the anti-depressants.  I'm beginning to feel like the med that supposed to help me feel better is making things worse.  Any ideas are appreciated!!!!

by Jasara, Jun 26, 2005 12:00AM
Effexor 75-150mg worked well for me as an anti-depressant that prevented weight gain. Actually think I lost weight on it and have been on it for 2 years now.

by Starzstuff, Jul 12, 2005 12:00AM
Parents have joined a mental health watchdog group asking the Food and Drug Administration (FDA) to investigate misleading advertising that could be forcing up drug sales and placing children at risk. They want the FDA to issue a warning letter to manufacturers—and, thereby, send a warning to psychiatric and patient groups they fund—that “Attention Deficit Hyperactivity Disorder” (ADHD)—and other mental disorders—cannot be promoted or advertised as “neurobiological” or caused by a “chemical imbalance” when scientific evidence does not support this. This follows a complaint last week to the FDA from 20 doctors, supported by actresses Kirstie Alley and Kelly Preston, urging stronger pediatric warnings on psychiatric drugs.

The complaint is one of many expected in light of the June 28, 2005 FDA warning that stimulants drugs prescribed to children can cause suicidal ideation, psychotic or violent behavior, and adverse cardiac effects. The FDA has already ordered a “black box” warning for antidepressant use in children because of suicidal reactions. Parents of adolescents who died or committed suicide while taking psychiatric drugs have supported the Citizens Commission on Human Rights (CCHR) in its submission to the FDA, urging them to provide information to consumers that psychiatric drugs do not “correct” any scientifically substantiated chemical imbalance or neurobiological psychiatric disorder.

Steven and Vicky Dunkle from Smethport, Pennsylvania, are still trying to come to grips with the death of their 10-year-old daughter, Shaina, on February 26, 2001. After being prescribed an amphetamine for “ADHD,” Shaina suffered a seizure in the doctor’s office. Mrs. Dunkle rushed to hold her, where, minutes later, she died. An autopsy determined that Shaina had died from drug toxicity. Today, the Dunkles are members of a nationwide parents’ group, ABLECHILD.org, who receive hundreds of complaints from parents that have been forced to put their child on a psychiatric drug—largely for “ADHD” that they thought was neurobiological or similar to a physical disease.

Advertising for “ADHD” stimulants has claimed the condition is a “neurobiological disorder” and the American Psychiatric Association on its website says that medications are prescribed because they “may correct imbalances in brain chemistry.” Yet in a recent media interview, APA president Steven Sharfstein said they have “no lab test” to determine this.

The National Institutes of Health advises there is no “valid test for ADHD; there are no data to indicate that ADHD is due to a brain malfunction.” The FDA agrees, “There is no biological test for ADHD.”

Dan and Celeste Steubing from Winchester, Virginia, testified before an FDA Hearing into antidepressants on September 13, 2004. In July 2003, their 18 year-old son, Matthew, had jumped to his death from the Cooper River Bridge in Charleston, South Carolina. He’d started taking an antidepressant, Lexapro, shortly before graduating from high school. “Matthew was a happy and healthy child with no prior history of depression…He loved sports, loud music, pretty girls, cool cars and Seinfeld…He had plans to join the Air Force ROTC program. He did not plan to die,” Mrs.Steubing testified.

In an interview with CCHR, available on its website, Mrs. Steubing says that when Matthew starting feeling disillusioned, a psychologist diagnosed him with a “chemical imbalance” causing depression and recommended an antidepressant. “How do they know it’s a chemical imbalance? They did no test, they did no blood test. They did nothing except listen to his symptoms and diagnosed him with a chemical imbalance. And treat him with a drug that killed him,” Mrs. Celeste says. “As parents, we have a right to make an informed decision regarding our child's care,” she told the FDA.

Dr. Karl Hoffower, a health care advisor to CCHR says: “Psychiatrists and ADHD organizations with pharmaceutical funding advertise ADHD as a ‘neurobiological disorder,’ which is false. I’ve treated children damaged by these drugs. Parents tell me that they agreed to the ‘medication’ because they were told it would correct a ‘chemical imbalance.’ There isn’t any medical or scientific means of proving ADHD or any other mental disorder is biologically based. It’s misleading at best and medical malpractice at worst.”

The International Narcotics Control Board has repeatedly warned the U.S. government that because of funding from ADHD drug manufacturers to psychiatric advocacy groups, this could be indirect advertising of methylphenidate (Ritalin). And this can drive up sales. Annual stimulant sales are $1.3 billion while antidepressant sales are at $14 billion.

by KittyMeghanLeah2, Jul 26, 2005 12:00AM
zoloft yep gain weight
paxil lost weight
wellbutrin not sure wasn't on it long enough
prozac lost weight

Mainly they made me gain weight except if it was prozac or paxil but they made me too wired and hyper.

I think it's different for everybody, remember everyone has a different "brain"

by deanna65, Aug 09, 2005 12:00AM
i have been on over 20 diff meds for depression in the past 8 years i have at this point gained 85 pounds the worst of which cymbolta which i have gained 30 pounds in 3 months!!!! i have tried to quit takin it b/c of this prob but i feel brain zaps almost like im here then im not seeing thingsas a movie i cant stand it!!! now i cant stand THE WAY ILOOK OR FEEL BOUT MYSELF the only one that feels better are the drug companies!!!!

by AmeerahAngel, Aug 10, 2005 12:00AM
I have huge issues with my weight. I have recently started seeing my Dr and she has said when I have my appointment on Friday this week she will discuss anti depressants with me. BUT I have heard that ALOT make you gain weight....and my eating issues are like 90% of my problem at the moment.

I dont know if you will be able to help really but i was wondering if there are any i can mention to her that make u gain weight that i definitly need to avoid? Or if there are any she may suggest that definitly dont make you gain ?

I really think If i get put on an anti depressant and gain weight it will just finish me off !

Thankyou :)

by AmeerahAngel, Aug 12, 2005 12:00AM
Ok I have already been now lol I think i posted a bit too late :)
Ive been put on  Escitalopram ive never heard of it lol but thats what im on 10mg so wel see how it goes

:)

by varuca, Aug 25, 2005 12:00AM
I have been on soooooooo many anti depressants and am getting quite sick of all the weight gain that comes with it. Weight gain is a depressing issue in itself.You would think that scientist would make an anti depressant that doesnt cause weight gain,I mean come on they can invent everything else!! I think people just dont care enough about people like us and think that depression and anxiety should be a much highly discust subject.Would someone pleeeeeeeeaaaaaaaase help all I do is eat chocolate,smoke and drink heaps of caffine.The question is IF ANTI DEPRESSANTS ARE STRONG ENOUGH TO MAKE ALL THOSE AWEFUL FEELINGS GO AWAY THEN WHY CANT THEY SUPRESS THE APPETITE? MMMMMMM MAKES YOU WONDER.

by varuca, Aug 25, 2005 12:00AM
I have been on soooooooo many anti depressants and am getting quite sick of all the weight gain that comes with it. Weight gain is a depressing issue in itself.You would think that scientist would make an anti depressant that doesnt cause weight gain,I mean come on they can invent everything else!! I think people just dont care enough about people like us and think that depression and anxiety should be a much highly discust subject.Would someone pleeeeeeeeaaaaaaaase help all I do is eat chocolate,smoke and drink heaps of caffine.The question is IF ANTI DEPRESSANTS ARE STRONG ENOUGH TO MAKE ALL THOSE AWEFUL FEELINGS GO AWAY THEN WHY CANT THEY SUPRESS THE APPETITE? MMMMMMM MAKES YOU WONDER.

by Younat, Sep 03, 2005 12:00AM
To: Anyone who is suffering...
I've tried every anti-depressant there is, and the only thing that has worked for me without major side effects was a daily dose of fish oil!

I strongly recommend anyone suffering from anxiety give fish oils a try. (I use Nordic Naturals Ultimate Omega capsules.)

From what I understand if one type of anti-depressant drug makes you gain weight, they all will.  I'm including Lexapro in that statement, too.

Paxil gave me the 'zappies' -- which persisted for over 5 months off the drug.  It made me gain weight.  Wellbutrin, too. Same thing.  Also, same with Celexa and Lexapro, although Lexapro's side effects were far more tolerable than other drugs I've been prescribed.

There are several recent clinical studies showing a far greater effectiveness with almost no side effects using fish oil to treat depression and anxiety over the use of traditional prescriptions.

(Of course, check with your doctor before changing your medication, and the studies I've seen dealing with fish oil have dealt only with anxiety, depression and bipolar disorders, and not other mental illnesses.)




by riya1, Sep 22, 2007 01:44PM
To: mcla
Hi! I haven't started taking zoloft yet, but I was prescribed for it by my docotor and you are the only person I seen say that it doesn't add on weight. Everyone says it puts weight on them and I'm trying to loose weight now by going to the gym and eating right! But I do need to start taking meds for my depression. Can you give me any advice and help on what I should do and more about your weight lost?.
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