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Mental Health  (Expert Forum)
 | 
Zoloft side effects
Answered by
Roger Gould, M.D. - Mental Health, Wellness
Questions posted in the Mental Health forum are being answered by Dr. Roger L. Gould, author of the Mastering Stress and Depression program and affiliated with the UCLA. Department of Psychiatry. Topics covered include anger, attention deficit disorder (ADD) , bipolar disorder , dementia , electroconvulsive therapy (ECT) , learning disabilities, memory, obsessive compulsive disorder (OCD) , panic , personality disorders, phobias , post-traumatic stress disorder (PTSD) , schizophrenia , stress , transitions, and work problems.

Zoloft side effects

by cnmt, Mar 14, 2003 12:00AM
I am a 38 yr old female.  I have suffered from severe post partum depression after each of my four children were born for which I was treated successfully with zoloft.  I took the drug for a period of one year for each episode and did very well on it.



It has been 3 yrs since I stopped taking zoloft and have been feeling very anxious recently and I feel like the depression is creaping back.  My doctor suggested I go back on the zoloft because it helped me so well in the past.  I have taken 25mg a day for the past past week and now I am experiencing a terrible salty taste in my mouth that is quite bothersome.  I didn't have this side effect in the past and am wondering if it could be the Zoloft and if so, will it eventually go away?



Thanks

by Roger Gould, M.D., Mar 17, 2003 12:00AM
A "salty taste" is not a side effect that is famiilar to me or reported in the literature, but 10-15% of people taking Zoloft do report a dry mouth, which does go away.  Perhaps your salty taste is secondary to a dry mouth.  If not, then zoloft is probably not the cause.
Member Comments (6)

by Skizo, Mar 15, 2003 12:00AM
To: cnmt
This is part of the Zoloft package insert.

-------------------------------------------------------

Treatment-Emergent Adverse Experience Incidence in

Placebo-Controlled Clinical Trials*

-----------------------------------------------------------------

                       Percent of Patients Reporting

                         Zoloft   Placebo  Difference

Adverse Experience       (N=861)  (N=853)  Percentage



Special Senses

Vision Abnormal            4.2      2.1     2.1

Tinnitus                   1.4      1.1     0.3

Taste Perversion           1.2      0.7     0.5

-----------------------------------------------------



In the table above 'salty taste' is in the "taste perversion" category.



I've heard similar complaint with the "old" antidepressants and also with Wellbutrin and Neurontin.



Try a mouth wash, this has helped some people. There are anecdotes about improvement with calcium, zinc etc. but I am not sure about this





by Skizo, Mar 15, 2003 12:00AM
To: cnmt
Sorry, the format of the table was distorted.

The point is that Zoloft does cause changes in the sense of taste.

by frecklesag29, Mar 16, 2003 12:00AM
To: skizo
Skizo,

Hope your weekend has gone well.  I need to ask you a question about effexor xr.  I have taken it for 2 1/2 months, 75mg a day.  I really don't see any results.  Although, I haven't thrown anything lately.  I still have the weird say the slightest thing negative and send me into crying spells.  I also still have a unusual fear and have experienced the numbness in the fingers ect.  Should I still be having these symptoms?  I have thought about just tapering off the med because it is quite costly if since I have not really seen any noticeable results.

Thanks

Hey

by Skizo, Mar 16, 2003 12:00AM
To: heyheyhey
The weekend went ok, thanks.



Obviously the medication is not working. The dose of Effexor XR you are taking is still in the lower side.  



One of the advantages of Effexor is that it works  in 2 different ways in the nervous system. At the dose you are taking it is more likely to be working only like a SSRI (Prozac-Paxil-Zoloft), to get the second effect (in the norepinephrine) you would have to take a higher dose.



In resistant depressions the combination of Effexor with Wellbutrin has worked pretty well.



I don’t know if you had the numbness in the fingers before Effexor. This medication is known to produce “paresthesias” (tingling and numbness).



Talk to your physician,.



Hope you feel better.



by frecklesag29, Mar 17, 2003 12:00AM
To: skizo
Thanks for the reply.
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