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Mental Health  (Expert Forum)
 | 
neurons § ssri § ecstasy
Answered by
Roger Gould, M.D. - Mental Health, Wellness
Questions posted in the Mental Health forum are being answered by Dr. Roger L. Gould, author of the Mastering Stress and Depression program and affiliated with the UCLA. Department of Psychiatry. Topics covered include anger, attention deficit disorder (ADD) , bipolar disorder , dementia , electroconvulsive therapy (ECT) , learning disabilities, memory, obsessive compulsive disorder (OCD) , panic , personality disorders, phobias , post-traumatic stress disorder (PTSD) , schizophrenia , stress , transitions, and work problems.

neurons § ssri § ecstasy

by cseymour, Feb 18, 2002 12:00AM
Hi:

Any comments on that research showing neuronal deformity
in lab animals who took large doses of SSRI's?  Also,
some anti-SSRI writers compare the drugs to MDMA, which the
medical establishment deems unsafe.  Do you think the
comparison is valid?

CS

by Roger Gould, M.D., Feb 19, 2002 12:00AM
I believe that the brain chemistry is so complex that are no definitive answers to your question. All we can do is go with the best evidence, and today the evidence is very strong that the ssri's are safe for long term use.  MDMA is a particularly dangerous drug because of its known, and frequent, cause of brain damage...there is no such reports of ssri's doing the same.
Member Comments (1)

by CCB, Feb 22, 2002 12:00AM
To: Cseymour
They both cause serotonin syndrome, when people die from taking extacy its from symptoms like rhabdomyolysis/hyperthermia that are caused by serotonin toxicity. Please if you can, send me names of authors of that literature so I can get a hold of the origional article.  Thankyou so much!

by GoatFace, Mar 18, 2002 12:00AM
All I can say from previous ecstacy use (no more...) is that paxil sure does feel like doing E (MDMA). Perhaps the extremeness of the happiness isn't there. But the physical symptons are incredibly similar. No surprise I guess seratonin is seratonin.
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