prozac

[all names taken]

I've known people on prozac, that quit cold turkey and had no withdrawal symtoms. I didn't have such luck with paxil,effexor.
Does prozac not have the withdrawal symtoms, is it not as likely to cause these problems?

[Roger Gould, M.D.]

Paxil is shorter acting and going cold turkey is almost impossible, whereas prozac is longer lasting, so stopping the oral medication means that you still have a blood level for longer and that gradually diminishes.

[Peagee]

Paxil is a clone of Prozac but with a shorter half-life.  Prozac leaves the body more slowly than Paxil.  Perhaps this site (social audit site) would help to explain it, its one of many sites but at a quick guess it will probably give you a lead to answering your question fairly quickly :)

http://www.socialaudit.org.uk/4200JOGL.htm#Prozac%20Backlash

There's tons of info on the net (and I mean professional experts' information - the internet harbours both good and bad sites).

There are support boards and info sites specifically with regard to SSRIs generally, some to Prozac, some to Paxil etc.  

Peagee
Now going offline :)

[Doggies4]

I have stopped taking 40 mg of Prozac cold turkey and I had no side effects, and I have done that several times over the years.  When I stopped taking Effexor, the side effects felt terrible.  Even tapering it down I still felt the side effects although to a lesser degree.

[SavingGrace]

Hello!  

One of my friends just directed me to this site.  Please read what 7,500 other folks have to say about Prozac:

http://www.PetitonOnline.com/lilpro

If you want to join a group who is looking for the truth about all of these drugs in the SSRI class (Prozac, Paxil, Zoloft,  Luvox, Celexa) please go to:

http://groups.yahoo.com/group/SSRI-Crusaders

We are a small group that is concerned that the whole truth about these drugs is not being given to the public.

Love to all,
Saving Grace

[Peagee]

List of clinical studies (summaries of 55 studies and results of antidepressants) can be found here:


http://www.network54.com/Hide/Forum/message?forumid=182310&messageid=1017830140

For more information on any of these, further searching will need to be done (using the title of the researhers/authors above each summary as a start?).  The summaries do give a fairly short but comprehensive list of the results.

Peagee :)

[JustSayNo]

Prozac is the easiest SSRI to withdraw from because it has such a long half-life that it slowly leaves your body.  Effexor is the hardest since it has the shortest half-life and one who is trying to taper will go in and out of withdrawal due to this.  Paxil is also very difficult to taper and withdraw from... Please see the Class Action Lawsuit against GlaxoSmithKline which address this lack of disclosure:

August 24, 2001

FOR IMMEDIATE RELEASE    

Baum, Hedlund, Aristei, Guilford & Schiavo
12100 Wilshire Blvd., Ste. 950
Los Angeles, CA 90025

Contact: Robin McCall, Media Relations
Day: [phone] or [phone]
Night: [phone]
Email: ***@****

Web: www.baumhedlundlaw.com

Victims File Lawsuit over Severe Withdrawal Reactions from the
Antidepressant, Paxil - First Class Action of its Kind Against an
Antidepressant Maker

Los Angeles, August 24, 2001 - - 35 people who have suffered from severe
withdrawal reactions as a result of taking the antidepressant Paxil, filed a
class action complaint today in California Superior Court, LA County,
against Glaxo Smithkline Corporation (GSK), formerly known as SmithKline
Beecham. This group represents thousands of Paxil users who have allegedly
suffered from withdrawal reactions and dependency/withdrawal syndrome. They
come from all walks of life (e.g., Lt. Col in the U.S. Air Force; former
star athlete; web-designer; children; bank fraud investigator and many more)
and reside throughout the United States. Each has experienced similar
withdrawal reactions and problems such as:

jolting electric "zaps," dizziness, light-headedness, vertigo,
in-coordination, gait disturbances, sweating, extreme nausea, vomiting, high
fever, abdominal discomfort, flu symptoms, anorexia, diarrhea, agitation,
tremulousness, irritability, aggression, sleep disturbance, nightmares,
tremor, confusion, memory and concentration difficulties, lethargy, malaise,
weakness, fatigue, paraesthesias, ataxia, and/or myalgia.

Paxil was introduced into the U.S. market on December 29, 1992, and is a
well known antidepressant medication in the same class as Zoloft and Prozac
(selective serotonin reuptake inhibitors or "SSRI's"). Paxil is approved for
marketing in the United States for conditions such as depression, obsessive
compulsive disorder, panic disorder, and "social anxiety disorder."

Complaint Allegations: 1) The complaint alleges Paxil can cause some people
who take it to experience serious and unexpected withdrawal reactions.
Neither the patients nor the physicians expect these withdrawal reactions
because, according to the complaint, the manufacturer has deliberately
failed to warn of their potential occurrence. Both physician and patient
unwittingly commit to Paxil without knowing the drug's addictive traits.
None of the named plaintiffs were ever informed before starting Paxil that
it was addictive, induced dependency, or created withdrawal reactions when
dosage was reduced or terminated.

2) Paxil creates both physical and psychological dependency because GSK has
suppressed the information about the severe withdrawal reactions of its
drug, many patients and their physicians are fooled into thinking that the
withdrawal reactions are caused by another condition (such as relapse), thus
prompting further incorrect and unnecessary medical treatment, including
increased dosages of Paxil.

3) GSK has known for years the distinct characteristics of Paxil which make
it prone to cause withdrawal reactions when discontinued. While the medical
community has acknowledged the potential for all SSRI's to cause
dependency/withdrawal syndrome, Paxil is, by far, the worst. According to
World Health Organization ("WHO") data obtained by the plaintiff class
members, Paxil has the highest incidence rate of withdrawal adverse
experiences of any antidepressant drug in the world. "Even despite our
clients' extreme difficulties caused by this drug, some remain on Paxil
today because they are "hooked" and fear they cannot get off the drug," says
attorney Mary Schiavo.

The complaint charges include fraud and deceit, negligence, strict
liability, breach of warranty and implied warranty which can be seen on the
complaint.

The lawsuit was filed by Karen Barth (in association with Mary Schiavo) of
Baum, Hedlund, Aristei, Guilford & Schiavo in Los Angeles and Donald Farber
of San Rafael, California.

The attorneys have stated, "The scariest part about this is that there are
people out there trying to get off this drug who are experiencing these
horrible withdrawal reactions. They think its because of something wrong
with them, when it's really the Paxil - - and then they take even more and
further exacerbate the problem!"

Fact Sheet is available on the web along with the complaint at
www.baumhedlundlaw.com.


DiscloseTheTruth

[Peagee]

CALIFORNIAN LAWSUIT re PAXIL can be found here:  

http://www.breggin.com/paxilcomplaint.html

and here are some extracts from it:

22.The "patient years" standard is a sham by anyone's common sense.It works like this.Assume 366 patients are selected at random to test Paxil.Three hundred and sixty five (365) patients take Paxil and suffer horribly the first day--immediately quitting the test.These patients are called, not surprisingly, "losers."The 366th patient, however, tolerates Paxil quite well, and even improves on the drug, staying in one or more trials for a full year.This patient is a "winner" by SKB standards.Like a champion race horse, this "winner" is entered in all the sweepstake trials for Paxil--and these trials are intentionally programmed to be long.Knowing they have a champion race horse, SKB racks up "points."By anyone's common sense standards, 365 failures out of 366 attempts would render the drug a dismal failure.But not so under "patient years."Under patient years, the one Paxil patient who tolerated the drug for one year counts the same as the 365 patients who couldn't tolerate the drug and dropped out the first day.The "score" in this example is "one patient year" for each side.Not surprisingly, the mathematicians who go along with this voodoo math are subordinate to the physicians and clinicians in the corporate chain of command, and the physicians at the top of the FDA chain of command.

23.In Paxil's clinical trials, SKB ultimately achieved positive results--as it were--because of emphasis on "subjective" testing data.Objective data is very scientific.Subjective data is less scientific.The latter requires more stringent controls to be applied scientifically.Subjective data is subject to the biases, opinions, and prejudices of the person(s) collecting the data.SKB’s subjective data to justify Paxil’s approval was obtained both from physicians, principal investigators ("PI") (most of whom were physicians) and from patients.The physicians and PI's were compensated handsomely by SKB for their participation in the trials.On information and belief, plaintiffs allege these individuals were hired only after appropriate screening to ensure they were friendly to the drug industry and SKB.

........28. In the meantime, SKB knew they had to keep a lid on the Yugoslavia trial to avoid detailed scrutiny by the FDA.SKB further knew that government regulators and mental health professionals were aware of the withdrawal issue and would look long and hard at any assertions SKB might claim in this area.SKB further knew that any claim connecting the "relapse" and "withdrawal" issues would be reviewed before the FDA committee that would vote on Paxil.Aware of this dilemma, SKB decided to massage the problem through back channel communications with Thomas Laughren, MD, a high official in the FDA.SKB felt if they could convince Dr. Laughren of the good "relapse" statistics in the Yugoslavia trial, they could avert the hard questioning of the FDA committee members on the withdrawal issue.Having "FDA" on your side before the FDA committee, it was felt, was good politics and a way to subtly shift responsibility for the issue away from SKB.To implement their tactic, SKB emphasized to Dr. Laughren that the Yugoslavia trial protocol was designed to detect relapse.At the same time, SKB told Laughren, they would do their best to detect and report on Paxil's withdrawal issues during Phase II.Given that "withdrawal" at that moment was not a front burner issue, that explanation satisfied the FDA official.


...32.At that juncture, SKB's plan for the committee was proceeding smoothly.The FDA was in their corner, and the FDA staff had told the committee exactly what SKB had hoped they would.Then in the afternoon it was SKB's turn to address the committee.SKB was not content to rest on Dr. Laughren's commentary regarding the Yugoslavia study.SKB boldly went to the next level.SKB asserted to the committee that SKB had studied "whether or not there is a discontinuation syndrome in patients who are abruptly discontinued from Paxil."The SKB representative continued:"To end with a brief discussion of whether or not there is a clear withdrawal syndrome, we have pulled upon the ...(Yugoslavia trial)..."Then, SKB made an outrageous and categorical falsehood.The SKB representative told the committee SKB in the Yugoslavia trial attempted to "systematically assess a discontinuation syndrome."This statement was in direct contradiction of Dr. Laughren's earlier statement in the day that "There was no systematic effort really to look at the withdrawal syndrome."Having refuted the FDA representation that there were no "systematic" tests on Paxil withdrawal, SKB then further claimed the tests were successful in that regard.The SKB representative told the committee they examined the data on the Phase II placebo group and that "few numbers of patients experienced any adverse event after being randomized off...(Paxil)...into the placebo group and the percentages are certainly very small."What SKB failed to add was that no "adverse events" were reported on the placebo group because the eighteen (18) placebo victims' symptoms were reported by SKB to have been "relapse" symptoms.Given the high bar established by SKB for relapse, the 18 placebo victims constituted a staggeringly high 45% of the placebo group.Had a reasonable clinical standard for "relapse" been set, it is quite possible 75% or 90% an or even higher casualty rate would have been recorded.

Lilly's "Prozac" and Pfizer's "Zoloft."In Paxil's first sales flyer, under the headline "Fewer Concerns," SKB boasted of the drug's "Minimal agitation...short half life and no potentially problematic metabolites.”Prozac and Zoloft both have considerably longer half-lives than Paxil; hence SKB uses the distinction to exploit what they view as Paxil’s advantage in that area.

41.Notwithstanding the Yugoslavia trial and the "Group of 108 Complaining Patients' Study," Paxil's short half life should have alerted SKB that Paxil would likely induce physical and psychological dependence, and create withdrawal problems for patients discontinuing or reducing its use.It is established scientific principle that short half-life substances are more likely to cause such dependency and withdrawal problems than substances with a long half-life.But SKB appeared oblivious to such a common scientific fact.SKB was and remains indifferent to Paxil's causal relationship to physical and psychological dependency, addiction, and withdrawal problems for Paxil patients desiring to discontinue or reduce dosage.

42.Paxil's labeling and prescribing information on "drug abuse and dependence" reported above deceived physicians and patients after December 29, 1992, similarly deceived from 1993 to 1999, and similarly deceives today.The deception rests with the fact that Paxil "hooks" many, many patients who have never had a "history of drug abuse."On information and belief, currently thousands of patients throughout the U.S. and hundreds of patients throughout California and Santa Clara County are "hooked" on Paxil because the labeling and prescribing information originated by SKB deceives physicians into believing the drug is not habit forming for most people when in fact it is.When the physicians and patients discover that Paxil does induce dependency, it is too late.Even though daily dosages for these Paxil patients are reduced incrementally from 30 mg or 40 mg down to 5 mg or 10 mg, the patient can go no further and must get his/her daily dosage or suffer major withdrawal symptoms as noted earlier in this complaint.The result of these terrible symptoms is for many patients to go back on Paxil.This terrible plight is no less than drug addiction induced by misleading information promulgated by SKB.


.....44.SKB's continuing sales advertising on print, radio, and TV on Paxil's short "half life" induces both physicians and patients to believe that Paxil has no withdrawal symptoms.In public promotion programs, SKB boasts that Paxil's short half life does not affect the therapeutic process and reduces side effects.The implication is that the short half is all good, and has no down sides.As a result, more and more patients are being prescribed Paxil, and are getting "hooked" on the drug.The physicians are as vulnerable as anyone.They are intellectual leaders in the community, but after they've been duped on such a basic issue and find their patient is "hooked" on Paxil, they remain silent out of embarrassment.They are also fearful of being sued for malpractice for their role; thus they remain silent as a group.

.....49.In addition to literally hundreds and thousands of known Paxil victims on an individual basis, SKB has also known for years that outside clinical studies conducted by prominent scientists have proven that Paxil causes withdrawal problems.

50.In 1993, CSM & MCA published a study indicating there were 78 reports of withdrawal symptoms on Paxil patients, that reactions tended to start 1-4 days after stopping the drug;

51.In 1994, Barr published a study on a 12-week double blind study indicating that several Paxil patients experienced withdrawal symptoms after abrupt discontinuation.It was further documented that in spite of dose tapering over 7-10 days, 3 out of 6 patients experienced withdrawal problems.

52.In 1994, Keithen reported that in spite of gradual dose reductions, 5 of 13 Paxil patients experienced withdrawal problems;

53.In 1994, Ellison reported 5% of SSRI patients reported peculiar and distinctive withdrawal phenomena.Ellison called it a "withdrawal buzz."It was further indicated in this study that SSRI's with longer half-lives would likely produce fewer and milder withdrawal symptoms.

54.In 1995, Block reported severe psychiatric symptoms associated with Paxil withdrawal in two middle-aged men.Neither had previously had a history of major psychiatric disorders.

55.In 1995, Debattista & Schatzberg reported Paxil patients stabilized on low dosages (10 mg daily) were abruptly withdrawn, whereupon the two (2) patients experienced symptoms including severe fatigue, dizziness, nausea and vomiting, headache, tremulousness and malaise.

56.In 1995, Fava & Grandi reported three (3) Paxil cases where depressed patients experienced withdrawal symptoms.

57.In 1995, Frost & Lall reported two (2) Paxil patients suffering withdrawal problems like severe "electric shock" like those cases previously reported by Ellison.

58.In 1995, Koopowitz and Berk reported a Paxil patient suffered severe dizziness and vertigo after abruptly stopping Paxil at 4 months.After four (4) days the patient was able to return to work, but brief episodes of the withdrawal symptoms persisted for one month.In another patient, severe and intolerable akathisia resulted after the patient had been taking Paxil for two (2) months, whereupon a severe withdrawal reaction followed, including vertigo, dizziness, ataxia, nausea, diplopia, heaviness in head, and feelings of dissociation.In a third case, a patient asked to stop medication after 6 months, in which the daily dosage for 20 mg daily.Dosage was then reduced to 10 mg daily for one month, and then to 10 mg on alternate days for two weeks.On alternate non-drug days the patient experienced severe headache, very severe nausea, dizziness and vertigo, dry mouth, and lethargy.The dose was then changed to 5 mg per day, but the patient felt gradual withdrawal prolonged her agony.She therefore stopped abruptly.She experienced two weeks of further withdrawal symptoms, but then fortunately recovered.

59.In 1995, Oerhberg published an article indicating that 19 patients out of 55 in a SKB sponsored study suffered withdrawal symptoms, much higher than the placebo portion of the clinical population.One SKB agent, when noting these statistics, commented that "only" 34.5% (19 of 55) reported withdrawal symptoms, but that such cases were only "of mild or moderate severity."

60.In 1995, Pyke reported a Paxil patient experienced flu like symptoms after discontinuing abruptly.Pyke reported deficiencies in SKB's prescribing information (as herein reported), but SKB did nothing about it.

61.In 1996, Bhuamilk Wildgust reported Paxil patients with learning disabilities were treated for depression either with Paxil (average 30 mg per day) or with Prozac (20 mg per day) on average for months.Withdrawal symptoms of agitation and restlessness were reported in 42% of the Paxil patients, but in no Prozac patients.

62.In 1996 Arya reported withdrawal symptoms in a female Paxil patient who had been treated with 20 mg daily for one year.On discontinuation, she reported headache, extreme tiredness, fatigue, emotional lability, a "floaty feeling" in her head and an inability to concentrate.She restarted Paxil at 10 mg daily and the symptoms disappeared.After one week, dosage was reduced to 5 mg daily for one week, and then Paxil was again stopped.Symptoms of tiredness, fatigue and "floaty feeling" returned and persisted for three days.

63.In 1996, Coupland reported a study involving 158 patients on SSRI's.In addition to Paxil--the SSRI's Prozac, Zoloft, and Luvox were studied.Severe withdrawal symptoms were noted for all.Symtpoms persisted for up to three (3) weeks.Symptoms occurred much more frequently with Paxil and Luvox than with the others.

64.In 1996, Mathew reported from Australia that severe withdrawal symptoms were noted in a study done there.Fifty one (51) different symptoms were observed, including "vivid dreams" and "lowered mood."The most common symptom, "dizziness," was variously described as having a "swimming, spaced-out, drunken or buzzing quality and was markedly exacerbated by movement."

65.In 1996, Pacheco reported five Paxil patients experienced withdrawal problems after treatment of 20 mg daily for 12-14 months, and the problems occurred notwithstanding a conservative tapering regimen.In two (2) of these cases, symptoms demanded urgent treatment.

66.In 1996 Reeves & Pinkofsky reported a 39 year old woman was being treated for depression.She took Paxil at 20 mg daily for one year.One day after abrupt withdrawal, she experienced nausea, hot and cold flashes, headaches, and lightheadedness, plus what she described as electric shocks running through her back and limbs, precipitated by movement.Symptoms worsened markedly over the next two days; electric shock sensations became so severe she began sitting as still as possible.At this point, the patient went to the hospital emergency room; withdrawal symptoms were reversed within three (3) hours of taking 20 mg of Paxil by the mouth.Later, she attempted gradual withdrawal (10 mg daily for one week), but the withdrawal symptoms re-appeared.Symptoms again abated when she resumed Paxil at 10 mg daily.The patient was subsequently withdrawn, with only minor and short lived symptoms, on 10 mg Paxil every other day for ten (10) days.

67.In 1997, nationally prominent psychiatrist Peter R. Breggin, in his "Brain Disabling Treatments in Psychiatry" published by Springer Publishing Co., reported withdrawal problems from Paxil and cited a 1995 Schatzberg report and 1994 Louie, Lannon, & Ajari report as bases for his conclusion.

68.In 1997, Dahl reported a suspected case of Paxil withdrawal in a neonate, following maternal exposure during the last trimester of pregnancy.The newborn initially appeared alert.At 12 hours, however, he was referred for observation of increased respiratory rate, jitteriness, increased muscle tone and tremor.Except for sustained jitteriness, symptoms decreased during the 3rd and 4th days, when close observation ceased.

69.In 1997, Landry and Roy, reported a 30 year old man on Paxil experienced withdrawal symptoms upon stopping Paxil a second time.He had stopped treatment earlier without ill effects, but the second time suffered severe withdrawal problems that lasted two (2) weeks.

70.In 1998, Huffstutler published an article reporting "discontinuation of antidepressant medications has received minimal attention" in the medical literature.

71.In 1998, McDonald reported 26 patients experienced withdrawal problems.These reactions were reported to the Canadian Adverse Drug Reactions Monitoring Programme for the four available SSRI's.Paxil was by far the worst, 17 of the 26 cases.Three (3) of the twenty six (26) cases (drug not specified), resulted in hospitalization or prolonged hospitalization; and in one case, "electric shock like" symptoms (paresthesia) persisted for four (4) years after discontinuation of Paxil.

72.In 1998, Rosenbaum and Fava published evidence about significant withdrawal problems associated with Paxil and Zoloft.

73.In 1999, Breggin again sounded the alarm on Paxil's withdrawal problems, joining with David Cohen in their book "Your Drug May Be Your Problem--How and Why to Stop Taking Psychiatric Medications."

74.In 1999, Bakker, published a letter in Dutch entitled "Severe withdrawal symptoms with fever upon stopping paroxetine...("Paxil" et al)..."

75.In 1999, Peeters & Zandbergen published a case history of a 30 year old man, who was treated for depression, and who experienced "violent withdrawal symptoms with fever upon stopping paroxetine...("Paxil" et al)..."

76.In 2000, "Psychiatry On-Line" reported two (2) patients who all suffered prolonged neurological symptoms for months after stopping Paxil."Mrs. F" continued to suffer from tardive dystonia, 8 months after stopping Paxil, and one (1) year after stopping Paxil, "Mr. B" still suffered intermittent episodes, lasting hours to days at a time, comprising paresthesiae, dizziness, unsteadiness and slurred speech.

77.On August 6, 2000, "Psychiatry Drug Alerts" published by M.J. Powers & Co., reported a controlled study of 107 patients in which Paxil patients suffered serious and many withdrawal problems, as opposed to Prozac and Zoloft patients who suffered little.It was stated "patients withdrawn from ...(Paxil)...reported deterioration in overall functioning and in functioning at work, relationships, and social activities.Patients withdrawn from...(Zoloft)...and...(Prozac)...reported lesser and no impairment, respectively."Powers hit the nail on the head on the seriousness of the "relapse vs withdrawal" issue.Powers added "a previous report has suggested that antidepressant withdrawal syndromes resolve within 1-2 weeks.Recognition and management of discontinuation symptoms is important, because these symptoms could be attributed to a depressive relapse or a physical illness (e.g. influenza) rather than to a specific drug interruption effect and may lead to pre-mature reinstitution of treatment."Whether Powers knew it or not, their study validates plaintiffs' allegations that SKB's Yugoslavia trial lead exactly to SKB's and FDA's wrong conclusions.Instead of providing validation on Paxil's addictive qualities, the Yugoslavia trial was improperly used as a vehicle to convince patients they needed continuous does of Paxil to cope with their depression.This was and is tragic, and must be stopped......


The complete lawsuit is too long to post here, but just as interesting as the above extracts. If you like thrillers full of power, money and corruption, this is a great read for you even if you're NOT on Paxil :)   Paula

[Peagee]

GSK - your corruption, duplicity and total lack of concern for human life is appalling. Worse than that of the Tobacco Company.  Worse than that of illegal Drug Dealers.  Worse than Alcohol manufacturers.  BECAUSE YOU maintain that your "mission is improving the quality of human life", here - on your website:
http://www.gsk.com
between the financial adverts on your page.

You make it difficult, almost impossible, for honest experts to speak out against you.  You use your money and dishonesty to corrupt wherever you can what were once decent human beings who took the Hippocratic Oath.  You "fund" and "treat" (or should I say Freebie and Bribe?) once ethical people.  You humiliate those who try to bring out the truth.  SHAME ON YOU.  What an awful reflection you give of our species.  Greedy, power-seeking, profit-searching, self interested, calculating people who will go to any lengths, walk over vulnerable children and adults, showing a total contempt for the quality of, or existence of, life.  And for what?  

FOR MONEY.  FOR POWER. FOR PERSONAL GAIN.

Here are just two of your innocent victims.
A little girl - died aged 12:
http://paxilsupport.homestead.com/kara.html

A little boy - died aged 11:
http://paxilsupport.homestead.com/othervictims.html

And there are, as you know, many many more.
How DARE you do this to human beings?

[heygirl]

please see my post  the other antidepressant thread.  Thyroid is the most misdiagnosed (ignored) issue in our culture today.  Many people have gotten off prozac etc when they get their thyroid supplimented.  Check the other thread for websites and discussion groups. Good luck!

[Peagee]

There's a lot of truth in what you say.  I'd just add that some  people who have been on SSRIs didn't have thyroid problems UNTIL they went on SSRIs.  SSRI's affect so many areas of the body - not only the brain and nervous system.  In case you haven't see the FDA list of Adverse Effects of Prozac (which is as you know an SSRI just as Celexa, Paxil, etc are) here it is (and thats an old list and reliant on the proportion of doctors who actually reported adverse effects):

"FDA Statistics (Gained through the Freedom Of Information Act)
~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
FDA REPORTED PROZAC CASES; TOTAL 35,230 (1987:-1995)
ALL FDA COSTART REACTION TERMS IN DATA ALPHABETICAL TERM ORDER - 04/10/96 -
~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

ABDO ENLARGE 35 ANEMIA MICROCYT 3
ABDO SYND ACUTE 9 ANEMIA NORMOCYT 3
ABORTION 96 ANEMIA REFRACT 1
ABSCESS 8 ANEURYSM INTRACRAN 5
ABSCESS BREAST 2 ANGINA PECTORIS 46
ABSCESS PERIODONT 1 ANGIOEDEMA 38
ACCOMMODATION ABNORM 4 ANISOCORIA 7
ACIDOSIS 15 ANOMALY CONGEN 202
ACIDOSIS DIABET 7 ANOMALY CONGEN CNS 3
ACIDOSIS LACTIC 1 ANOMALY CONGEN MS 3
ACIDOSIS RESP 4 ANOMALY CONGEN RESP 1
ACNE 80 ANOMALY HEART 2
ADAMS STOKES SYND 2 ANOMALY VASCUL 8
ADDISON CRISIS 1 ANOREXIA 396
ADENOMA 15 ANORGASMIA 566
ADENOMA THYR 1 ANTICHOLINERG SYND 12
ADH INAPPROP 85 ANTICOAG DEC 2
ADREN INSUFFIC 3 ANTICOAG INC 7
AGITATION 1191 ANTISOCIAL REACT 8
AGRANULOCYTOSIS 18 ANURIA 6
AKATHISIA 299 ANXIETY 1153
AKINESIA 8 APATHY 105
ALBUMINURIA 25 APHASIA 27
ALCOHOL INTOLER 45 APNEA 59
ALKALOSIS 1 APPETITE INC 105
ALKALOSIS RESP 4 APPLICAT SITE REACT 4
ALLERG REACT 151 ARRHYTHMIA 107
ALOPECIA 696 ARRHYTHMIA ATR 3
ALTERED DRUG LEVEL 3 ARRHYTHMIA NOD 2
ALTERED HORMONE LEVE 28 ARRHYTHMIA VENT 7
ALTERED NEUROTR LEVE 8 ARTERIOSCLEROSIS 18
AMBLYOPIA 188 ARTERIOSPASM 1
AMENORRHEA 129 ARTERITIS 6
AMNESIA 557 ARTHRALGIA 479
AMYLASE INC 23 ARTHRITIS 117
ANA 93 ARTHRITIS RHEUMAT 14
ANAPHYL 39 ARTHROSIS 79
ANEMIA 99 ASCITES 7
ANEMIA APLAST 14 ASPHYXIA 11
ANEMIA B12 DEFIC 4 ASTHENIA 788
ANEMIA FOLIC DEFIC 1 ASTHMA 97
ANEMIA HEMOL 17 ATAXIA 124
ANEMIA HEMOL DCN 1 ATAXIA CEREBELL 4
ANEMIA HEMOL DCP 4 ATELECTASIS 3
ANEMIA HEMOL ICP 1 ATROPHY MUSCLE 2
ANEMIA HYPOCHROM 32 ATROPHY OPTIC 2
ANEMIA IRON DEFIC 12 ATROPHY SKIN 3
ANEMIA MACROCYT 4 ATROPHY TESTIS 4
ANEMIA MEGALOBLAST 6 AV BLOCK 11
AV BLOCK COMP 13 CEREBROVASC DIS 10
AV BLOCK FD 6 CERVICITIS 1
AV BLOCK SD 4 CERVIX DIS 1
BARBITUR INTOX 2 CHEILITIS 2
BILIRUBINEM 68 CHILLS 96
BILIRUBINURIA 1 CHILLS FEVER 39
BIRTH PREMAT 26 CHLOASMA 1
BIRTH WEIGHT SUBNORM 2 CHOLANGITIS 3
BLEED TIME INC 44 CHOLECYST 24
BLEPHARITIS 8 CHOLELITH 20
BLIND 23 CHOLINERG SYND 1
BLIND COLOR 3 CHOREOATHETOSIS 15
BLIND NIGHT 2 CHROMATOPSIA 2
BLOOD DYSCRASIA 7 CHROMOSOME ABNORM 1
BODY ODOR 11 CINCHONISM 1
BONE DIS 10 CLITORIS ENLARGE 4
BONE FRACT SPONTAN 77 CNS DEPRESS 11
BRADYCARDIA 133 CNS STIMULAT 53
BRADYCARDIA SINUS 16 COAGUL DIS 25
BRAIN STEM DIS 3 COAGUL TIME INC 3
BRAIN SYND ACUTE 45 COGWHEEL RIGID 45
BRAIN SYND CHRON 16 COLITIS 34
BREAST ENGORGE 5 COLITIS HEM 2
BREAST ENLARGE 65 COLITIS PSEUDOMEM 3
BREAST FIBROCYST 26 COLITIS ULCER 15
BRONCHIOLITIS 3 COLLAGEN DIS 2
BRONCHITIS 57 COMA 181
BUCCOGLOSSAL SYND 126 COMA DIABET 3
BUN INC 11 COMA HEPATIC 3
BUNDLE BRANCH BLOCK 25 CONFUS 591
BURSITIS 8 CONJUNCTIVITIS 39
CACHEXIA 8 CONSTIP 79
CAPILL FRAGIL INC 2 CONVULS 642
CARCINOMA 30 CONVULS GRAND MAL 275
CARCINOMA BLADDER 1 COOMBS DIR TEST POS 1
CARCINOMA BREAST 22 COORDINAT ABNORM 118
CARCINOMA CERVIX 3 COR PULM 2
CARCINOMA ENDOMETR 3 CORNEAL LESION 8
CARCINOMA GI 17 CORNEAL OPACITY 4
CARCINOMA LIVER 2 CORONARY ART DIS 22
CARCINOMA LUNG 9 COUGH INC 132
CARCINOMA PROSTATE 3 CRAMPS LEG 25
CARCINOMA SKIN 12 CREATINE PK INC 65
CARCINOMA THYR 1 CREATININE CLEAR DEC 2
CARDIOMEGALY 5 CREATININE INC 25
CARDIOMYOPATHY 12 CSF ABNORM 5
CARDIOSPASM 5 CUSHINGS SYND 4
CARDIOVASC DIS 57 CYANOSIS 12
CATARACT 43 CYST 43
CATARACT NOS 1 CYSTITIS 24
CATATON REACT 36 DEAF 82
CELLULITIS 12 DEAF PERM PART 2
CEREBELL SYND 1 DEAF TRANS PART 4
CEREBROVASC ACCID 109 DEAF TRANS TOTAL 1
DEATH 121 EDEMA LARYNX 19
DEHYDRAT 37 EDEMA LUNG 48
DELIRIUM 123 EDEMA PERIPH 191
DELUSIONS 80 EDEMA RETINAL 2
DEMENTIA 36 EDEMA SCROTUM 1
DEPERSONAL 159 EDEMA TONGUE 62
DEPRESSION 1111 EEG ABNORM 52
DEPRESSION PSYCHOTIC 1205 EFFUS PERICARD 1
DERM CONTACT 16 EFFUS PLEURAL 25
DERM EXFOL 23 EJACULAT ABNORM 281
DERM FUNG 11 ELECTROLYTE ABNORM 11
DERM LICHEN 11 ELECTROLYTE DEPLET 2
DERMATOMYOSITIS 2 EMB 5
DIABETES INSIPID 1 EMB CEREBR 3
DIABETES MELL 25 EMB LEG 1
DIARRHEA 517 EMB PULM 51
DIARRHEA BLOODY 26 EMOTION LABIL 271
DIC 2 EMPHYSEMA 4
DIGITALIS INTOX 3 ENCEPHALITIS 2
DIPLOPIA 42 ENCEPHALOP HYPERTENS 2
DISCOLOR TONGUE 22 ENCEPHALOPATHY 27
DISCOLOR TOOTH 6 ENDO DIS 4
DIZZINESS 636 ENDOCARD 3
DREAM ABNORM 437 ENDOMETR DIS 6
DRUG DEPEND 90 ENTERITIS 2
DRUG DEPEND ADDICT 35 ENZYME ABNORM 15
DRUG INTERACTION 733 EOSINOPHILIA 42
DRUG LEVEL DEC 33 EPIDERM NECRO 8
DRUG LEVEL INC 265 EPIDIDYMITIS 8
DRY EYE 22 EPISTAXIS 69
DRY MOUTH 114 ERUCTAT 12
DUODENITIS 1 ERYTHEMA MULT 44
DYSARTHRIA 25 ERYTHEMA NOD 19
DYSKINESIA 45 ESOPHAGITIS 55
DYSKINESIA TARDIVE 72 ESR INC 71
DYSMENORRHEA 16 EUPHORIA 110
DYSPAREUNIA 3 EXOPHTHALMOS 7
DYSPEPSIA 202 EXTRAPYR SYND 270
DYSPHAGIA 69 EXTRASYSTOLES 9
DYSPNEA 333 EXTRASYSTOLES BIGEM 18
DYSTONIA 151 EXTRASYSTOLES SUPVEN 8
DYSURIA 50 EXTRASYSTOLES VENT 50
EAR DIS 20 EYE DIS 55
ECCHYMOSIS 437 FACIES MASK 14
ECG ABNORM 68 FEMININE 1
ECZEMA 15 FERTIL DEC FEM 3
EDEMA 100 FERTIL DEC MALE 13
EDEMA BRAIN 10 FERTIL INC FEM 4
EDEMA FACE 174 FETAL DIS 11
EDEMA GENERAL 46 FEVER 358
EDEMA INJECT SITE 1 FEVER MALIGNANT 13
EDEMA LABIA 1 FIBRILLAT ATR 42
FIBRILLAT VENT 23 HEALING ABNORM 4
FIBRIN INC 1 HEART ARREST 96
FIBRINOGEN DEC 1 HEART BLOCK 10
FIBRINOGEN INC 1 HEART FAIL 60
FIBRO LUNG 39 HEART FAIL LEFT 4
FIBRO MESENTER 1 HEART FAIL RIGHT 44
FIBRO RETROPERIT 3 HEM 81
FIBRO TENDON 2 HEM CEREBR 12
FLATUL 80 HEM COLON 2
FLU SYND 149 HEM ESOPH 3
FLUTTER ATR 6 HEM EYE 38
FOOT DROP 7 HEM GI 66
FURUNCULOSIS 7 HEM GUM 14
GAIT ABNORM 142 HEM INTRACRAN 5
GANGRENE 2 HEM LUNG 2
GANGRENE INTEST 2 HEM MUSCLE 2
GANGRENE PERIPH 1 HEM POSTPARTUM 1
GASTRITIS 39 HEM PREGN 8
GASTRITIS HEM 1 HEM RECTAL 34
GASTROENTERITIS 15 HEM RETINAL 18
GGTP INC 63 HEM RETROPERIT 1
GI DIS 124 HEM SUBARACHNOID 9
GINGIVITIS 26 HEM UTER 19
GLAUCOMA 34 HEM VAGINAL 65
GLOBULIN DEC 1 HEMATEMESIS 15
GLOBULIN INC 2 HEMATOMA SUBDURAL 4
GLOBULIN INC GAMMA 2 HEMATURIA 84
GLOMERULITIS 4 HEMIPLEGIA 31
GLOSSITIS 53 HEMOCHROMATO 2
GLUCOCORT INC 4 HEMOLYSIS 3
GLUCOSE TOLER DEC 3 HEMOPERITON 2
GLYCOSURIA 4 HEMOPTYSIS 19
GOITER 13 HEMOSIDERO 1
GONADOTR DEC FSH 2 HEMOTHORAX 1
GONADOTR DEC LH 2 HEPATITIS 98
GONADOTR INC 1 HEPATITIS C 1
GONADOTR INC FSH 8 HEPATITIS HBSAG 2
GONADOTR INC LH 4 HEPATOMA 2
GOUT 8 HEPATOMEGALY 13
GRANULOMA 3 HEPATORENAL SYND 4
GRANULOMA SKIN 1 HEPATOSPLENOMEGALY 2
GROWTH ACCELER 2 HERNIA 12
GROWTH RETARD 2 HERPES SIMPLEX 30
GUILLAIN BARRE SYND 6 HERPES ZOSTER 24
GYNECOMASTIA 26 HICCUP 14
HAIR DIS 26 HIRSUTISM 33
HAIR DISCOLOR 9 HIV SYND 4
HALITOSIS 5 HIV TEST POS 2
HALLUCIN 482 HOSTILITY 999
HANGOVER 9 HYDROCEPHALUS 3
HDL DEC 3 HYDRONEPHROSIS 2
HEADACHE 1187 HYPER GUM 3
HEADACHE VASC 7 HYPERACUSIS 1
HYPERALGESIA 1 INFECT 101
HYPERCALCEM 9 INFECT BACT 1
HYPERCHLORHYDRIA 2 INFECT SUPER 1
HYPERCHOLESTEREM 93 INFECT URIN TRACT 53
HYPERESTHESIA 17 INFECT VIRAL 2
HYPERGLYCEM 88 INJECT SITE REACT 1
HYPERKALEM 13 INJURY ACCID 307
HYPERKINESIA 202 INJURY INTENT 502
HYPERLIPEM 46 INSOMNIA 1334
HYPERNATREM 7 INTEST LARGE PER 2
HYPERPLASIA ENDOMETR 5 INTEST PER 1
HYPERTENS 407 INTRACRAN HYPERTENS 11
HYPERTENS PULM 5 IRITIS 7
HYPERTHYR 42 ISCHEMIA CEREBR 20
HYPERTONIA 268 ISCHEMIA MYOCARD 12
HYPERTROPHY 1 JAUNDICE 56
HYPERTROPHY SKIN 4 JAUNDICE CHOLESTAT 29
HYPERURICEM 6 JAUNDICE NEONAT 1
HYPERVENTIL 43 JOINT DIS 75
HYPESTHESIA 50 KERATITIS 5
HYPOCALCEM 9 KERATOCONJUNCTIVITIS 7
HYPOCHLOREM 7 KETOSIS 9
HYPOCHOLESTEREM 4 KIDNEY CALCULUS 35
HYPOGLYCEM 145 KIDNEY FAIL 51
HYPOGLYCEM REACT 11 KIDNEY FAIL ACUTE 16
HYPOKALEM 73 KIDNEY FUNC ABNORM 14
HYPOKINESIA 40 KIDNEY POLYCYSTIC 1
HYPOMAGNESEM 1 KIDNEY TUBUL DIS 1
HYPOMENORRHEA 6 LAB TEST ABNORM 93
HYPONATREM 460 LAB TEST INTERFER 31
HYPOPROTEINEM 5 LABOR ABNORM 22
HYPOTENS 146 LACRIMATION DIS 18
HYPOTENS POST 84 LACTATION DEC 1
HYPOTHERMIA 18 LACTATION FEM 269
HYPOTHYR 94 LACTATION MALE 3
HYPOTONIA 10 LARYNGISMUS 36
HYPOVENTIL 10 LARYNGITIS 10
HYPOVOLEM 1 LDH INC 50
HYPOXIA 25 LE SYND 70
HYSTERIA 28 LE TEST ABNORM 4
ILEITIS 6 LEUKEMIA 6
ILEUS 5 LEUKEMIA ACUTE 5
IMMUNE SYSTEM DIS 5 LEUKEMIA ACUTE LYMPH 2
IMMUNOGLOBUL INC 2 LEUKEMIA ACUTE MYELO 1
IMPACT FECAL 1 LEUKOCYTOSIS 81
IMPOTENCE 243 LEUKODERMA 8
INCONTIN FECAL 29 LEUKOPENIA 191
INCONTIN URIN 122 LEUKOPLAKIA ORAL 2
INCREASED EFFECT 29 LEUKORRHEA 9
INFARCT CEREBR 14 LIBIDO DEC 677
INFARCT MYOCARD 122 LIBIDO INC 102
INFARCT PULM 1 LIPASE INC 1
LIPODYSTROPHY 1 MYOPATHY 20
LIVER CIRRHO 14 MYOSITIS 28
LIVER DAMAGE 35 NAIL DIS 22
LIVER FAIL 26 NASAL SEPTUM DIS 1
LIVER FATTY 20 NAUSEA 971
LIVER FUNC ABNORM 389 NAUSEA VOMIT 248
LIVER TENDER 4 NAUSEA VOMIT DIAR 40
LUNG DIS 41 NECK RIGID 39
LUNG FUNC DEC 4 NECRO 2
LYMPHADENO 79 NECRO BONE 13
LYMPHEDEMA 1 NECRO INTEST 4
LYMPHOCYTOSIS 8 NECRO KIDNEY PAPILL 1
LYMPHOMA LIKE REACT 15 NECRO KIDNEY TUBUL 2
MALABSORP SYND 1 NECRO LIVER 8
MALAISE 167 NECRO SKIN 2
MANIC DEPRESS REACT 30 NEOPL 18
MANIC REACT 553 NEOPL BLADDER 5
MARROW DEPRESS 17 NEOPL BREAST 11
MASTITIS 3 NEOPL CNS 7
MED ERROR 24 NEOPL LARYNX 1
MEGACOLON 1 NEOPL SKIN 8
MEGAKARYO DEC 1 NEOPL THYR 1
MEGAKARYO INC 1 NEOPL UTER 1
MELANOMA SKIN 4 NEPHRITIS 7
MELANOSIS 3 NEPHROSCLEROSIS 1
MELENA 23 NEPHROSIS 8
MENINGISM 2 NERVOUSNESS 1193
MENINGITIS 5 NEURALGIA 19
MENOPAUSE 15 NEURITIS 5
MENORRHAGIA 69 NEURITIS OPTIC 26
MENS DIS 110 NEURITIS PERIPH 31
MENTAL RETARD 4 NEURITIS RETROBULBAR 1
METHEMOGLOBIN 1 NEUROLEPTIC MALSYND 54
METRORRHAGIA 111 NEUROPATHY 59
MIGRAINE 108 NEUROSIS 158
MIOSIS 1 NO DRUG EFFECT 743
MONILIA 4 NOCTURIA 10
MONILIA GI 2 NODULE SKIN 8
MONILIA ORAL 6 NODULE SUBCUTAN 15
MONILIA SKIN 1 NPN INC 4
MONILIA VAGINA 3 NYSTAGMUS 24
MONOCYTOSIS 2 OBESITY 3
MONOPLEGIA 1 OBSTRUCT INTEST 15
MOVEMENT DIS 59 OCCLUS 4
MUCOUS MEM DIS 6 OCCLUS CAROTID 2
MYALGIA 266 OCCLUS CORONARY 8
MYASTHENIA 72 OCCLUS MESENTER 2
MYDRIASIS 66 OCCLUS MESENTER ART 1
MYELOFIBROSIS 2 OCCLUS RETINAL ART 1
MYELOMA 1 OCULOGYRIC CRISIS 24
MYELOPROLIF DIS 1 OLIGURIA 16
MYOCARDITIS 2 OPISTHOTONOS 6
MYOCLONUS 163 ORCHITIS 2
OSTEOMYELITIS 2 PHARYNGITIS 131
OSTEOPOROSIS 11 PHLEB 11
OSTEOPOROSIS FRACT 2 PHOSPHATASE ALK INC 84
OTITIS EXT 1 PHOTOPHOBIA 31
OTITIS MED 7 PHOTOSENSITIVITY 126
OVAR DIS 30 PIT ACTIV DEC 4
OVERDOSE 768 PIT ACTIV INC 7
OVERDOSE ACCID 87 PLACENTA DIS 7
OVERDOSE INTENT 652 PLAT ABNORM 14
OVULAT FAIL 1 PLAT ADHESIVE DEC 1
PAIN 345 PLEURAL DIS 5
PAIN ABDO 394 PNEUMONIA 150
PAIN BACK 98 PNEUMONIA ASPIR 15
PAIN BIL 2 PNEUMONIA EOSINOPHIL 7
PAIN BONE 33 PNEUMONIA INTERSTIT 18
PAIN BREAST 70 PNEUMOTHORAX 3
PAIN CHEST 247 POLYARTERITIS NODOSA 2
PAIN CHEST SUBSTERN 7 POLYCYTHEMIA 6
PAIN EAR 20 POLYNEURITIS 3
PAIN EYE 61 POLYURIA 21
PAIN INJECT SITE 1 PORPHYRIA 9
PAIN KIDNEY 3 PR PROLONGED 3
PAIN NECK 47 PREGN DIS 12
PAIN PELVIC 19 PREGN MULT 3
PAIN URETHRA 10 PREGN TEST FALSE POS 3
PALLOR 13 PREGN TOXEMIA 2
PALPITAT 212 PREGN UNINTEND 1021
PANCREAS DIS 3 PRIAPISM 45
PANCREATITIS 59 PROCTITIS 1
PANCYTOPENIA 22 PROCTITIS ULCER 1
PAP SMEAR SUSP 3 PROLACTIN INC 129
PAPILLEDEMA 8 PROSTAT DIS 23
PARALYSIS 23 PROTHROMBIN DEC 77
PARALYSIS EXTRAOCUL 5 PROTHROMBIN INC 14
PARALYSIS FACIAL 26 PRURITUS 686
PARALYSIS FLACCID 2 PSA INC 1
PARALYSIS SPASTIC 3 PSORIASIS 24
PARALYSIS VOCAL CORD 4 PSYCHOSIS 269
PARANOID REACT 192 PTOSIS 11
PARAPLEGIA 1 PUPIL DIS 5
PARATHYR DIS 2 PURPURA 50
PARESTH CIRCUMORAL 27 PURPURA THROMBOPEN 35
PARESTHESIA 430 PURPURA THROMBOPEN T 3
PAROSMIA 20 PURPURA VASC 4
PAROTID ENLARGE 7 PYELONEPHRITIS 5
PENIS DIS 25 PYURIA 3
PEPTIC ULCER SYND 3 QT PROLONGED 40
PERICARDITIS 4 RASH 1753
PERINATAL DIS 8 RASH LE 6
PERIOST DIS 1 RASH MAC PAP 185
PERITONITIS 5 RASH PETECH 21
PERSON DIS 574 RASH PURPUR 19
PETECHIA 33 RASH PUST 16
RASH VESIC BULL 86 SPUTUM INC 3
RBC ABNORM 15 ST DEPRESSED 5
RE BLOCK 1 ST ELEVATED 2
RE HYPERPLASIA 1 STENO AORTIC 1
REACT AGGRAV 868 STENO BLADDER 3
REACT UNEVAL 120 STENO PYLOR 3
RECTAL DIS 14 STEVENS JOHNSONSYND 13
REFLEXES DEC 7 STILLBIRTH 11
REFLEXES INC 24 STOMACH ATONY 1
REFRACT DIS 9 STOMACH DILAT 1
RESPIRAT DIS 72 STOMATITIS 52
RESPIRAT DISTRES SYN 2 STOMATITIS APHTH 6
RETINAL DEGENERAT 9 STOMATITIS ULCER 6
RETINAL DETACH 2 STOOL ABNORM 9
RETINAL DIS 10 STRABISMUS 2
RETINAL PIGMENT 1 STRIDOR 6
RETINAL VASC DIS 4 STUPOR 137
RHABDO 1 SUDDEN DEATH 38
RHINITIS 75 SUICIDE ATTEMPT 2246
SALICYLISM 1 SWEAT 429
SALIV GLAND ENLARGE 12 SWEAT DEC 1
SALIVA INC 27 SYNCOPE 335
SALPINGITIS 5 SYNOVITIS 2
SARCOIDOSIS 3 SYPH TEST FALSE POS 1
SCHIZOPHRENIC REACT 20 T INVERTED 8
SCLERITIS 3 TACHYCARDIA 333
SCLERODERMA 3 TACHYCARDIA SUPVENT 29
SCLEROSIS MULT 18 TACHYCARDIA VENT 65
SCREAMING SYND 7 TASTE LOSS 23
SEBORRHEA 7 TASTE PERVERS 71
SEPSIS 23 TENDON DIS 12
SERUM IRON INC 4 TENDON RUPT 2
SERUM SICK 80 TENESMUS 3
SEX FUNC ABNORM 25 TENOSYNOVITIS 70
SEX MAT ACCEL 2 TESTIS DIS 17
SGOT INC 168 TETANY 6
SGPT INC 155 THINKING ABNORM 652
SHOCK 30 THIRST 25
SINUSITIS 28 THROM 12
SKIN DIS 25 THROM CAROTID 1
SKIN DISCOLOR 69 THROM CEREBR 3
SKIN DRY 29 THROM CEREBR VEN 1
SKIN STRIAE 2 THROM CORONARY 2
SLEEP DIS 83 THROM PULM 1
SOMNOLENCE 1029 THROM RETINAL VEIN 3
SPASM GENERAL 9 THROMBOCYTHEM 26
SPEECH DIS 189 THROMBOCYTOPENIA 145
SPERM ARREST 1 THROMBOPHLEB 22
SPLEEN DIS 1 THROMBOPHLEB DEEP 12
SPLEEN RUPT 3 THROMBOPLASTIN DEC 13
SPLENOMEGALY 7 THYR DIS 28
THYROIDITIS 8 URIN RETENT 162
TINNITUS 220 URIN TRACT DIS 14
TOLER DEC 3 URIN URGENCY 23
TOLER INC 166 URTICARIA 595
TONGUE DIS 15 UTER ATONY 1
TOOTH CARIES 1 UTER DIS 7
TOOTH DIS 92 UTER ENLARGE 2
TORSADES DE POINTES 8 UTER FIBROID DEGEN 1
TORTICOLLIS 21 UTER FIBROID ENLARGE 8
TRANSPOS GREAT VESS 1 UTER RUPT 2
TREMOR 798 UTER SPASM 2
TRISMUS 76 VAGINITIS 38
TWITCH 323 VASC DIS 5
UG DIS 3 VASC DIS PERIPH 25
ULCER CORNEAL 1 VASCULITIS 62
ULCER DUODEN 6 VASCULITIS KIDNEY 2
ULCER DUODEN HEM 7 VASODILAT 230
ULCER DUODEN PER 2 VEIN VARICOSE 6
ULCER ESOPH 5 VERTIGO 76
ULCER INTEST 1 VESTIBUL DIS 9
ULCER MOUTH 46 VISION ABNORM 201
ULCER PEPTIC 8 VISUAL FIELD DEFECT 3
ULCER PEPTIC HEM 5 VITREOUS DIS 9
ULCER PEPTIC REACT 2 VOICE ALTERAT 26
ULCER SKIN 20 VOMIT 180
ULCER STOMACH 12 VULVOVAGINAL DIS 5
ULCER STOMACH HEM 8 VULVOVAGINITIS 2
ULCER STOMACH PER 1 WATER INTOX 2
UNEXPECTED BENEFIT 244 WBC ABNORM 9
UREMIA 2 WEIGHT DEC 507
URETHRITIS 8 WEIGHT INC 533
URICACIDUR 1 WITHDRAW SYND 329
URIN ABNORM 26 YAWN 71
URIN FREQUENCY 110
URIN IMPAIRED 23
_______________________________________________________
TOTAL INCIDENCES: 64992
TOTAL TERMS: 902 (from 35,230 cases)
* WARNING!! The incidence counts do NOT represent ADR (Adverse Reaction Reports) counts. Each ADR filed with the FDA may have have from 1 to 5 reaction terms recorded per report/case.
Food & Drug Administration, Freedom of Information Staff (HFI-35),
Center for Drug Evaluation and Research, 5600 Fishers Lane, Rockville,MD 20857 Telephone [phone]


Quite a list hmm?  Paula :)