Dear Kathy
Serzone (Nefozodone) is a medication that has been approved for the treatment of depression. Clinical reports indicate that Serzone may be an effective treatment for depression accompanied by anxiety disorders such as panic disorder, Obsessive Compulsive disorder etc. When Serzone and Xanax are taken together, Xanax levels are increased by approximately 2 fold. So it is recommended to reduce the Xanax dosage by 50% if it administered along with Serzone.
I would recommend that you discuss with your Physician/ Psychiatrist in detail about your concerns. I hope this information is helpful to you