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Mental Health  (Expert Forum)
 | 
switching from Citalapram to Venlafaxine
Answered by
Roger Gould, M.D. - Mental Health, Wellness
Questions posted in the Mental Health forum are being answered by Dr. Roger L. Gould, author of the Mastering Stress and Depression program and affiliated with the UCLA. Department of Psychiatry. Topics covered include anger, attention deficit disorder (ADD) , bipolar disorder , dementia , electroconvulsive therapy (ECT) , learning disabilities, memory, obsessive compulsive disorder (OCD) , panic , personality disorders, phobias , post-traumatic stress disorder (PTSD) , schizophrenia , stress , transitions, and work problems.

switching from Citalapram to Venlafaxine

by Skelly88, Oct 02, 2009 02:39PM
okay, So i just got my prescription for vanlafaxine, i'm nervous about taking it though.  I've always been afraid to take new medicines, and this one is an SNRI as opposed to a SSRI which I was taking I believe.  whats the difference? should I worry? and is it safe to take the vanlafaxine so soon after stopping the citalapram? i just took my last citalapram yesterday around this time.  Anyways, i'm nervous, any advice?

by Roger Gould, M.D., Oct 02, 2009 05:28PM
To: skelly88
You have to rely on your doctor to determine if this is safe for you..in general, yes it is safe.  There are other medications for anxiety like klonopin. You should ask your doctor about that if you are nervous about what has been prescribed.
Member Comments (7)

by Paxiled, Oct 02, 2009 05:02PM
First question:  did you taper off?  Meaning, are you having any withdrawal symptoms?  if so, best to wait them out before starting a new med so you'll be able to tell which are side effects from the new med and which are withdrawal effects from the old.  Makes it easier to evaluate what's happening.  The difference is, an ssri targets serotonin receptors, while an snri targets both serotonin and norepinephrine receptors.  Serotonin plays a role in both depression and anxiety, while norepinephrine is kind of like one of the body's "uppers" that stimulates the down that depressed people have.  If you don't suffer from depression, this could be stimulating and make you more anxious, so just be on the lookout for that.  Quitting can also be difficult, so when you're ready for that, make sure you're properly prepared and your shrink is properly prepared.  Good luck.  And I'm not the doctor.

by Skelly88, Oct 02, 2009 05:17PM
To: Paxiled
I didnt technically taper off citalopram, i didnt take it regularly like I should which I know is bad.  
I dont know about the depression, but I do know that I get really bad anxiety attack..so now i'm worried about taking it, i dont wanna have anxiety attack worse than what I already do.. my muscles are already always tense and it doesn't take much to give me a panic attack. so idk.. :(  i'm worried.  

by Skelly88, Oct 02, 2009 05:45PM
Okay, i've been doing some reading, and from what I can find, the XR version can be given for panic disorder.  Does this mean that the regular (non XR version) isn't effective for panic disorder?

by Jaquta, Oct 04, 2009 08:09PM
My understanding is that they are antidepressants used to treat depression and/ or GAD.  I don't pay much attention to medication anymore (as I rarely take them) but they are just different brand names or generics.  ??  Some meds are sustained release too.
Meds can be way to complex for us lay people and that's just one reason why we go to doctors.  It's good to be informed though and it's good to challenge things we don't understand or have concerns about.

Medications sometimes don't work if you take them differently from how they are prescribed.
I was very non-compliant with meds (and I wondered why I was still anxious and depressed.  Homer would say Duh!).

If you're anxious about taking the medication then you should discuss that with your doctor.  The doctor is there to help you.
In the past when I was put on medication I was extremely anxious and I was prescribed clonazepam (klonopin) (in addition to the other med) to help with that.

I hope you are able to get on top of your anxiety/ panic.  The med should help with the muscle tension too.

by Paxiled, Oct 05, 2009 02:57AM
Don't pay any attention to what these meds are approved for.  All ssris and snris technically treat the same things, it's just that to get FDA approval a new drug has to act differently than an older one.  Most pharma companies just research one thing, but once they get approval, doctors use them for whatever they feel like.  Example:  Prozac was the first ssri, so it got approved for depression, but has always also been used for anxiety since serotonin affects both.  When Zoloft came out, it also was approved for depression but also did some studies on anxiety to differentiate it from Prozac.  When Paxil came out, it did some studies on panic disorder.  Luvox focused on OCD.  See how it works?  It's all a game, really.  Unfortunately.

by Jaquta, Oct 05, 2009 04:57PM
Many doctors use meds off-label too.  They may use a medication for something else entirely than what it was intended for.
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