Bone tumor of the skull with headache, PLEASE RESPOND

Hello, I have a 3.5 centimeter bone tumor in the left supraorbital region of my skull that has not grown or changed since its discovery.   I had CT and MRI follow ups, and a nuclear bone scan also, that lead to the diagnosis of monostotic fibrous dysplasia of the skull although I did not have a biopsy.    My symptoms have been moderate to intense pressure behind my forehead that has not changed since 4 years ago.      Recently, I met with a new ENT who suggested high dose bisphosphonate therapy and referred me to an endocrinologist for this.    I have read reports online that 40 mg/day Fosamax,   or Reclast infusions have helped people with fibrous dysplasia in the skull and headaches.     Can you comment on this therapy at all?    What if I have this therapy, for example,  and it's really not fibrous dysplasia but is another type of tumor such as intraosseous meningioma for example, could this make my condition/symptoms worse by worsening the ossification?   There are so many quesitons on my mind,  please comment?

[DrNoopurMD]

Hi,

Thanks for writing in.
You are right biphophonates like fosamax help in conditions where is bone weakening by reducing the activity of osteoclast cells which destroy bones. Usually radiological investigations like CT scan or MRI are sufficient to make the exact diagnosis.
Since you have undergone these investigations already and are diagnosed with a monostotic variety which is a milder variety as compared to polyostotoc ones, you can consider this therapy. However for your satisfaction you can seek a second opinion.
Keep us posted!